STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RF_0544Efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (331 aa)    
Predicted Functional Partners:
tolC
Type I secretion outer membrane protein, TolC family.
 
 0.934
acrF
Hydrophobe/amphiphile efflux-1 HAE1 family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.898
RF_0643
RND efflux system, outer membrane protein.
 
 
 0.884
RF_0641
RND family efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.874
RF_0640
RND family efflux transporter.
 
 
 0.868
RF_0639
RND family efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.854
lolD
Lipoprotein releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
  
 
 0.753
mfp
Membrane-fusion protein component of the RND family transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 
0.665
polA
DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.535
emrA
Multidrug resistance protein A.
 
   
 0.419
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
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