STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mpgDNA-3-methyladenine glycosidase; Belongs to the DNA glycosylase MPG family. (177 aa)    
Predicted Functional Partners:
RF_0561
Unknown.
       0.774
RF_0562
Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
       0.774
RF_0915
Methylated-DNA--protein-cysteine methyltransferase.
  
  
 0.767
dat
Methylated-DNA--protein-cysteine methyltransferase.
  
  
 0.767
xth2
Exodeoxyribonuclease III.
    
 0.707
xth1
Exodeoxyribonuclease III.
    
 0.707
pheT
Phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
    0.571
nuoE
NADH dehydrogenase I chain E; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
       0.528
polA
DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.474
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.