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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tlpAThiol:disulfide interchange protein TlpA. (215 aa)    
Predicted Functional Partners:
tdpX1
Thioredoxin peroxidase 1.
  
 0.993
lpdA2
Dihydrolipoamide dehydrogenase.
  
 0.948
lpdA1
Dihydrolipoamide dehydrogenase.
  
 0.948
nrdA
Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.922
gltD
NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
  
 0.892
RF_0047
Cell surface antigen-like protein Sca10.
  
 0.892
RF_0960
Sco2 protein precursor; Belongs to the SCO1/2 family.
 
 
 0.879
RF_0043
Sco2 protein precursor; Belongs to the SCO1/2 family.
 
 
 0.856
RF_0044
Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.
   
 
 0.839
coxB
Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).
   
 
 0.839
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
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