iscR protein (Rickettsia felis) - STRING interaction network

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[Homology]

Score

iscR

Iron-sulfur cluster assembly transcription factor IscR. (139 aa)

Predicted Functional Partners:

spl1

0.969

iscU

0.966

iscS

0.934

hscB

0.904

iscA2

0.873

RF_0874

0.809

fdxB

0.635

iscA1

0.429

Your Current Organism:

Rickettsia felis

NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RF_0874	iscR	RF_0874	RF_0847	Unknown.	Iron-sulfur cluster assembly transcription factor IscR.	0.809
RF_0874	iscU	RF_0874	RF_0844	Unknown.	FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.	0.629
fdxB	hscB	RF_1064	RF_1062	Ferredoxin; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions; Belongs to the adrenodoxin/putidaredoxin family.	Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.	0.985
fdxB	iscA1	RF_1064	RF_0111	Ferredoxin; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions; Belongs to the adrenodoxin/putidaredoxin family.	Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.	0.634
fdxB	iscA2	RF_1064	RF_0843	Ferredoxin; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions; Belongs to the adrenodoxin/putidaredoxin family.	Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.	0.924
fdxB	iscR	RF_1064	RF_0847	Ferredoxin; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions; Belongs to the adrenodoxin/putidaredoxin family.	Iron-sulfur cluster assembly transcription factor IscR.	0.635
fdxB	iscS	RF_1064	RF_0845	Ferredoxin; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions; Belongs to the adrenodoxin/putidaredoxin family.	Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.	0.948
fdxB	iscU	RF_1064	RF_0844	Ferredoxin; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions; Belongs to the adrenodoxin/putidaredoxin family.	FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.	0.992
fdxB	spl1	RF_1064	RF_0846	Ferredoxin; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions; Belongs to the adrenodoxin/putidaredoxin family.	Nifs protein homolog.	0.958
hscB	fdxB	RF_1062	RF_1064	Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.	Ferredoxin; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions; Belongs to the adrenodoxin/putidaredoxin family.	0.985
hscB	iscA1	RF_1062	RF_0111	Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.	Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.	0.833
hscB	iscA2	RF_1062	RF_0843	Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.	Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.	0.962
hscB	iscR	RF_1062	RF_0847	Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.	Iron-sulfur cluster assembly transcription factor IscR.	0.904
hscB	iscS	RF_1062	RF_0845	Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.	Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.	0.898
hscB	iscU	RF_1062	RF_0844	Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.	FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.	0.995
hscB	spl1	RF_1062	RF_0846	Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.	Nifs protein homolog.	0.877
iscA1	fdxB	RF_0111	RF_1064	Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.	Ferredoxin; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions; Belongs to the adrenodoxin/putidaredoxin family.	0.634
iscA1	hscB	RF_0111	RF_1062	Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.	Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.	0.833
iscA1	iscR	RF_0111	RF_0847	Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.	Iron-sulfur cluster assembly transcription factor IscR.	0.429
iscA1	iscS	RF_0111	RF_0845	Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.	Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.	0.775