close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ntrXNitrogen assimilation regulatory protein NtrX; Member of the two-component regulatory system RF_0895/RF_0427. (475 aa)    
Predicted Functional Partners:
ntrY
Nitrogen regulation protein NtrY; Member of the two-component regulatory system RF_0427/RF_0895.
 
 0.993
RF_0815
Na+/proline symporter and signal transduction histidine kinase; Sodium:solute symporter family, SSF.
  
 
 0.812
RF_0896
Uncharacterized low-complexity protein; COG1357.
  
    0.798
RF_1281
Conserved hypothetical protein.
 
  
 0.789
RF_1043
Conserved hypothetical protein.
 
  
 0.787
envZ
Osmolarity sensor protein EnvZ.
 
 
 0.733
RF_1175
TPR repeats.
   
 
 0.731
barA
Histidine kinase sensor protein.
  
 
 0.710
RF_0047
Cell surface antigen-like protein Sca10.
  
  
 0.629
dksA
DnaK suppressor protein homolog; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.
 
  
 0.613
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.