STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RF_0896Uncharacterized low-complexity protein; COG1357. (589 aa)    
Predicted Functional Partners:
ntrX
Nitrogen assimilation regulatory protein NtrX; Member of the two-component regulatory system RF_0895/RF_0427.
  
    0.798
virB6_5
TrbL/VirB6 plasmid Conjugative transfer protein.
  
     0.742
sca1
Cell surface antigen Sca1; 212 kDa.
 
    0.673
RF_0053
Putative surface antigen.
  
    0.625
gcvT
Glycine cleavage T-protein; Aminomethyl transferase; Belongs to the GcvT family.
  
     0.573
ubiH
2-polyprenyl-6-methoxyphenol 4-hydroxylase.
  
     0.562
virB6_3
TrbL/VirB6 plasmid Conjugative transfer protein.
  
     0.476
virB6_4
TrbL/VirB6 plasmid Conjugative transfer protein.
  
     0.465
virB6_1
TrbL/VirB6 plasmid Conjugative transfer protein.
  
     0.456
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.435
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
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