Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tolCType I secretion outer membrane protein, TolC family. (454 aa)    
Predicted Functional Partners:
aprE
Alkaline protease secretion protein AprE; Type I secretion membrane fusion protein, HlyD family.
 
 
 0.951
RF_0643
RND efflux system, outer membrane protein.
  
  
 0.944
RF_0544
Efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.934
mfp
Membrane-fusion protein component of the RND family transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.919
emrA
Multidrug resistance protein A.
  
 
 0.909
RF_0986
Unknown.
 
     0.876
RF_0987
Ankyrin repeat.
 
   
 0.808
aprD
Alkaline protease secretion ATP-binding protein AprD; ABC transporter.
 
  
 0.800
ompW
OmpW family outer-membrane protein.
  
   
 0.729
virD4
VirD4 protein.
  
   
 0.660
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
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