rne protein (Rickettsia felis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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[Homology]

Score

rne

Ribonuclease E. (678 aa)

Predicted Functional Partners:

pnp

0.935

RF_0263

0.751

RF_0264

0.751

topA

0.673

rho

0.653

polA

0.603

rnc

0.547

RF_1175

0.545

bamD

0.537

pcnB

0.531

Your Current Organism:

Rickettsia felis

NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RF_0263	RF_0264	RF_0263	RF_0264	ATP-dependent RNA helicase RhlE.	ATP-dependent RNA helicase RhlE.	0.987
RF_0263	pnp	RF_0263	RF_0721	ATP-dependent RNA helicase RhlE.	Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.	0.917
RF_0263	rho	RF_0263	RF_0765	ATP-dependent RNA helicase RhlE.	Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.	0.438
RF_0263	rnc	RF_0263	RF_1176	ATP-dependent RNA helicase RhlE.	Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.	0.582
RF_0263	rne	RF_0263	RF_1025	ATP-dependent RNA helicase RhlE.	Ribonuclease E.	0.751
RF_0264	RF_0263	RF_0264	RF_0263	ATP-dependent RNA helicase RhlE.	ATP-dependent RNA helicase RhlE.	0.987
RF_0264	pnp	RF_0264	RF_0721	ATP-dependent RNA helicase RhlE.	Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.	0.917
RF_0264	rho	RF_0264	RF_0765	ATP-dependent RNA helicase RhlE.	Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.	0.438
RF_0264	rnc	RF_0264	RF_1176	ATP-dependent RNA helicase RhlE.	Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.	0.582
RF_0264	rne	RF_0264	RF_1025	ATP-dependent RNA helicase RhlE.	Ribonuclease E.	0.751
RF_1175	pcnB	RF_1175	RF_0019	TPR repeats.	Poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.	0.549
RF_1175	polA	RF_1175	RF_1239	TPR repeats.	DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.696
RF_1175	rnc	RF_1175	RF_1176	TPR repeats.	Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.	0.736
RF_1175	rne	RF_1175	RF_1025	TPR repeats.	Ribonuclease E.	0.545
RF_1175	topA	RF_1175	RF_0530	TPR repeats.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.638
bamD	polA	RF_1088	RF_1239	Unknown; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.	DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.567
bamD	rne	RF_1088	RF_1025	Unknown; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.	Ribonuclease E.	0.537
pcnB	RF_1175	RF_0019	RF_1175	Poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.	TPR repeats.	0.549
pcnB	pnp	RF_0019	RF_0721	Poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.	Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.	0.829
pcnB	polA	RF_0019	RF_1239	Poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.	DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.695