emrA protein (Rickettsia felis) - STRING interaction network

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Score

emrA

Multidrug resistance protein A. (355 aa)

Predicted Functional Partners:

emrB

0.968

RF_0643

0.945

tolC

0.909

pssA

0.793

RF_1217

0.730

clpB

0.686

RF_1218

0.669

manC

0.623

rpoZ

0.618

RF_1041

0.524

Your Current Organism:

Rickettsia felis

NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RF_0643	emrA	RF_0643	RF_1044	RND efflux system, outer membrane protein.	Multidrug resistance protein A.	0.945
RF_0643	emrB	RF_0643	RF_1124	RND efflux system, outer membrane protein.	Multidrug resistance protein B; MFS type drug exporter; Belongs to the major facilitator superfamily.	0.493
RF_0643	tolC	RF_0643	RF_0985	RND efflux system, outer membrane protein.	Type I secretion outer membrane protein, TolC family.	0.944
RF_1041	emrA	RF_1041	RF_1044	Conserved hypothetical protein.	Multidrug resistance protein A.	0.524
RF_1041	pssA	RF_1041	RF_1045	Conserved hypothetical protein.	CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.524
RF_1217	RF_1218	RF_1217	RF_1218	Unknown.	Unknown.	0.977
RF_1217	emrA	RF_1217	RF_1044	Unknown.	Multidrug resistance protein A.	0.730
RF_1217	emrB	RF_1217	RF_1124	Unknown.	Multidrug resistance protein B; MFS type drug exporter; Belongs to the major facilitator superfamily.	0.606
RF_1218	RF_1217	RF_1218	RF_1217	Unknown.	Unknown.	0.977
RF_1218	emrA	RF_1218	RF_1044	Unknown.	Multidrug resistance protein A.	0.669
clpB	emrA	RF_0150	RF_1044	ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to the ClpA/ClpB family.	Multidrug resistance protein A.	0.686
clpB	emrB	RF_0150	RF_1124	ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to the ClpA/ClpB family.	Multidrug resistance protein B; MFS type drug exporter; Belongs to the major facilitator superfamily.	0.618
clpB	rpoZ	RF_0150	RF_0944	ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to the ClpA/ClpB family.	DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.673
emrA	RF_0643	RF_1044	RF_0643	Multidrug resistance protein A.	RND efflux system, outer membrane protein.	0.945
emrA	RF_1041	RF_1044	RF_1041	Multidrug resistance protein A.	Conserved hypothetical protein.	0.524
emrA	RF_1217	RF_1044	RF_1217	Multidrug resistance protein A.	Unknown.	0.730
emrA	RF_1218	RF_1044	RF_1218	Multidrug resistance protein A.	Unknown.	0.669
emrA	clpB	RF_1044	RF_0150	Multidrug resistance protein A.	ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to the ClpA/ClpB family.	0.686
emrA	emrB	RF_1044	RF_1124	Multidrug resistance protein A.	Multidrug resistance protein B; MFS type drug exporter; Belongs to the major facilitator superfamily.	0.968
emrA	manC	RF_1044	RF_0241	Multidrug resistance protein A.	Mannose-1-phosphate guanylyltransferase.	0.623