close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
emrAMultidrug resistance protein A. (355 aa)    
Predicted Functional Partners:
RF_0643
RND efflux system, outer membrane protein.
 
 
 0.953
emrB
Multidrug resistance protein B; MFS type drug exporter; Belongs to the major facilitator superfamily.
 
 
 0.945
tolC
Type I secretion outer membrane protein, TolC family.
  
 
 0.854
pssA
CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.783
RF_1217
Unknown.
 
 
 0.690
RF_1218
Unknown.
  
 
 0.620
manC
Mannose-1-phosphate guanylyltransferase.
  
  
 0.616
lolD
Lipoprotein releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
  
 
 0.583
mfp
Membrane-fusion protein component of the RND family transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.533
RF_1043
Conserved hypothetical protein.
       0.525
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
Server load: low (20%) [HD]