pbpC protein (Rickettsia felis) - STRING interaction network

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Score

pbpC

Bifunctional penicillin-binding protein 1C. (774 aa)

Predicted Functional Partners:

RF_0887

0.956

pbpA1

0.929

mrcA

0.924

pbpA2

0.913

dacF

0.900

RF_1070

0.737

topA

0.562

Your Current Organism:

Rickettsia felis

NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RF_0887	pbpC	RF_0887	RF_1069	Large extracellular alpha-helical protein.	Bifunctional penicillin-binding protein 1C.	0.956
RF_1070	pbpC	RF_1070	RF_1069	Unknown.	Bifunctional penicillin-binding protein 1C.	0.737
dacF	mrcA	RF_0609	RF_1276	Penicillin-binding protein DacF precursor; Belongs to the peptidase S11 family.	Penicillin-binding protein 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.942
dacF	pbpA1	RF_0609	RF_0900	Penicillin-binding protein DacF precursor; Belongs to the peptidase S11 family.	Penicillin-binding protein.	0.941
dacF	pbpA2	RF_0609	RF_0902	Penicillin-binding protein DacF precursor; Belongs to the peptidase S11 family.	Penicillin-binding protein.	0.953
dacF	pbpC	RF_0609	RF_1069	Penicillin-binding protein DacF precursor; Belongs to the peptidase S11 family.	Bifunctional penicillin-binding protein 1C.	0.900
mrcA	dacF	RF_1276	RF_0609	Penicillin-binding protein 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Penicillin-binding protein DacF precursor; Belongs to the peptidase S11 family.	0.942
mrcA	pbpA1	RF_1276	RF_0900	Penicillin-binding protein 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Penicillin-binding protein.	0.958
mrcA	pbpA2	RF_1276	RF_0902	Penicillin-binding protein 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Penicillin-binding protein.	0.978
mrcA	pbpC	RF_1276	RF_1069	Penicillin-binding protein 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Bifunctional penicillin-binding protein 1C.	0.924
pbpA1	dacF	RF_0900	RF_0609	Penicillin-binding protein.	Penicillin-binding protein DacF precursor; Belongs to the peptidase S11 family.	0.941
pbpA1	mrcA	RF_0900	RF_1276	Penicillin-binding protein.	Penicillin-binding protein 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.958
pbpA1	pbpA2	RF_0900	RF_0902	Penicillin-binding protein.	Penicillin-binding protein.	0.934
pbpA1	pbpC	RF_0900	RF_1069	Penicillin-binding protein.	Bifunctional penicillin-binding protein 1C.	0.929
pbpA1	topA	RF_0900	RF_0530	Penicillin-binding protein.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.507
pbpA2	dacF	RF_0902	RF_0609	Penicillin-binding protein.	Penicillin-binding protein DacF precursor; Belongs to the peptidase S11 family.	0.953
pbpA2	mrcA	RF_0902	RF_1276	Penicillin-binding protein.	Penicillin-binding protein 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.978
pbpA2	pbpA1	RF_0902	RF_0900	Penicillin-binding protein.	Penicillin-binding protein.	0.934
pbpA2	pbpC	RF_0902	RF_1069	Penicillin-binding protein.	Bifunctional penicillin-binding protein 1C.	0.913
pbpA2	topA	RF_0902	RF_0530	Penicillin-binding protein.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.507