| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RF_0047 | RF_1111 | RF_0047 | RF_1111 | Cell surface antigen-like protein Sca10. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.491 |
| RF_0047 | polA | RF_0047 | RF_1239 | Cell surface antigen-like protein Sca10. | DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.692 |
| RF_0047 | tme | RF_0047 | RF_0584 | Cell surface antigen-like protein Sca10. | Malate oxidoreductase and phosphate acetyltransferase. | 0.655 |
| RF_1111 | RF_0047 | RF_1111 | RF_0047 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Cell surface antigen-like protein Sca10. | 0.491 |
| RF_1111 | RF_1112 | RF_1111 | RF_1112 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Unknown; Belongs to the SDHAF4 family. | 0.575 |
| RF_1111 | RF_1113 | RF_1111 | RF_1113 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Unknown. | 0.575 |
| RF_1111 | gidB | RF_1111 | RF_0118 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Predicted S-adenosylmethionine-dependent methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.514 |
| RF_1111 | ksgA | RF_1111 | RF_0256 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.480 |
| RF_1111 | manC | RF_1111 | RF_0241 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Mannose-1-phosphate guanylyltransferase. | 0.511 |
| RF_1111 | polA | RF_1111 | RF_1239 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.608 |
| RF_1111 | queF | RF_1111 | RF_0057 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Unknown; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.589 |
| RF_1111 | rsmI | RF_1111 | RF_1194 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.481 |
| RF_1111 | tme | RF_1111 | RF_0584 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Malate oxidoreductase and phosphate acetyltransferase. | 0.498 |
| RF_1112 | RF_1111 | RF_1112 | RF_1111 | Unknown; Belongs to the SDHAF4 family. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.575 |
| RF_1112 | RF_1113 | RF_1112 | RF_1113 | Unknown; Belongs to the SDHAF4 family. | Unknown. | 0.847 |
| RF_1113 | RF_1111 | RF_1113 | RF_1111 | Unknown. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.575 |
| RF_1113 | RF_1112 | RF_1113 | RF_1112 | Unknown. | Unknown; Belongs to the SDHAF4 family. | 0.847 |
| gidB | RF_1111 | RF_0118 | RF_1111 | Predicted S-adenosylmethionine-dependent methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.514 |
| gidB | ksgA | RF_0118 | RF_0256 | Predicted S-adenosylmethionine-dependent methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.469 |
| gidB | manC | RF_0118 | RF_0241 | Predicted S-adenosylmethionine-dependent methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | Mannose-1-phosphate guanylyltransferase. | 0.516 |