sdhA protein (Rickettsia felis) - STRING interaction network

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sdhA

Succinate dehydrogenase flavoprotein subunit. (596 aa)

Predicted Functional Partners:

sdhB

0.999

sdhD

0.999

sdhC

0.999

fumC

0.998

sucD

0.992

sucC

0.992

nuoF

0.969

petA

0.964

nuoG

0.959

gabD

0.954

Your Current Organism:

Rickettsia felis

NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
fumC	gabD	RF_0273	RF_0684	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Succinate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.972
fumC	nuoG	RF_0273	RF_1262	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 75 kDa subunit family.	0.544
fumC	petA	RF_0273	RF_1010	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis; Belongs to the Rieske iron-sulfur protein family.	0.423
fumC	sdhA	RF_0273	RF_1159	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Succinate dehydrogenase flavoprotein subunit.	0.998
fumC	sdhB	RF_0273	RF_0136	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.	0.978
fumC	sdhC	RF_0273	RF_1163	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Succinate dehydrogenase cytochrome b-556 subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH).	0.957
fumC	sdhD	RF_0273	RF_1161	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).	0.923
fumC	sucC	RF_0273	RF_0665	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.765
fumC	sucD	RF_0273	RF_0664	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	Succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.826
gabD	fumC	RF_0684	RF_0273	Succinate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.972
gabD	nuoG	RF_0684	RF_1262	Succinate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 75 kDa subunit family.	0.480
gabD	sdhA	RF_0684	RF_1159	Succinate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Succinate dehydrogenase flavoprotein subunit.	0.954
gabD	sdhB	RF_0684	RF_0136	Succinate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.	0.941
gabD	sdhC	RF_0684	RF_1163	Succinate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Succinate dehydrogenase cytochrome b-556 subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH).	0.908
gabD	sdhD	RF_0684	RF_1161	Succinate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).	0.909
gabD	sucC	RF_0684	RF_0665	Succinate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.637
gabD	sucD	RF_0684	RF_0664	Succinate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.532
nuoF	nuoG	RF_1178	RF_1262	NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 51 kDa subunit family.	NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 75 kDa subunit family.	0.998
nuoF	petA	RF_1178	RF_1010	NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 51 kDa subunit family.	Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis; Belongs to the Rieske iron-sulfur protein family.	0.967
nuoF	sdhA	RF_1178	RF_1159	NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 51 kDa subunit family.	Succinate dehydrogenase flavoprotein subunit.	0.969