Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
htrAPeriplasmic serine protease; Belongs to the peptidase S1C family. (513 aa)    
Predicted Functional Partners:
hflC2
Membrane protease subunits; HflC and HflK could regulate a protease.
  
 
 0.849
RF_0024
Unknown.
   
 
 0.737
RF_0421
Unknown.
   
 
 0.737
hflK
Protease activity modulator HflK; HflC and HflK could encode or regulate a protease.
  
 
 0.635
sca4
Cell surface antigen; 114 kDa; gene D.
      
 0.618
omp
17 kDa surface antigen precursor.
      
 0.618
gltA
Citrate synthase I.
      
 0.618
groEL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.608
fadB
3-hydroxyacyl-CoA dehydrogenase FadB; In the C-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
    
 0.601
rompB
Outer membrane protein B; Cell surface antigen Sca5, 168 kDa.
      
 0.568
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
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