hflC2 protein (Rickettsia felis) - STRING interaction network

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Score

hflC2

Membrane protease subunits; HflC and HflK could regulate a protease. (286 aa)

Predicted Functional Partners:

hflK

0.996

ftsH

0.931

htrA

0.849

mpp

0.750

engB

0.643

coxB

0.642

RF_0044

0.555

mrp

0.542

miaA

0.538

yidC

0.510

Your Current Organism:

Rickettsia felis

NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RF_0044	hflC2	RF_0044	RF_1167	Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.	Membrane protease subunits; HflC and HflK could regulate a protease.	0.555
RF_0044	hflK	RF_0044	RF_1168	Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.	Protease activity modulator HflK; HflC and HflK could encode or regulate a protease.	0.555
coxB	ftsH	RF_0629	RF_0139	Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).	ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.	0.557
coxB	hflC2	RF_0629	RF_1167	Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).	Membrane protease subunits; HflC and HflK could regulate a protease.	0.642
coxB	hflK	RF_0629	RF_1168	Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).	Protease activity modulator HflK; HflC and HflK could encode or regulate a protease.	0.642
coxB	mpp	RF_0629	RF_0338	Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).	Mpp; Similar to mitochondrial protease.	0.859
coxB	yidC	RF_0629	RF_0131	Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).	Preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.	0.911
engB	hflC2	RF_0085	RF_1167	Hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.	Membrane protease subunits; HflC and HflK could regulate a protease.	0.643
engB	yidC	RF_0085	RF_0131	Hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.	Preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.	0.786
ftsH	coxB	RF_0139	RF_0629	ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.	Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).	0.557
ftsH	hflC2	RF_0139	RF_1167	ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.	Membrane protease subunits; HflC and HflK could regulate a protease.	0.931
ftsH	hflK	RF_0139	RF_1168	ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.	Protease activity modulator HflK; HflC and HflK could encode or regulate a protease.	0.968
ftsH	miaA	RF_0139	RF_0714	ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.	tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.	0.486
ftsH	mpp	RF_0139	RF_0338	ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.	Mpp; Similar to mitochondrial protease.	0.598
ftsH	yidC	RF_0139	RF_0131	ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.	Preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.	0.464
hflC2	RF_0044	RF_1167	RF_0044	Membrane protease subunits; HflC and HflK could regulate a protease.	Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.	0.555
hflC2	coxB	RF_1167	RF_0629	Membrane protease subunits; HflC and HflK could regulate a protease.	Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).	0.642
hflC2	engB	RF_1167	RF_0085	Membrane protease subunits; HflC and HflK could regulate a protease.	Hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.	0.643
hflC2	ftsH	RF_1167	RF_0139	Membrane protease subunits; HflC and HflK could regulate a protease.	ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.	0.931
hflC2	hflK	RF_1167	RF_1168	Membrane protease subunits; HflC and HflK could regulate a protease.	Protease activity modulator HflK; HflC and HflK could encode or regulate a protease.	0.996