gmk protein (Rickettsia felis) - STRING interaction network

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Score

gmk

Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (192 aa)

Predicted Functional Partners:

rpoZ

0.972

ndk

0.945

spoT15

0.934

nrdA

0.920

nrdB

0.905

spoT7

0.903

spoT8

0.903

spoT1

0.903

spoT9

0.903

spoT3

0.903

Your Current Organism:

Rickettsia felis

NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
gmk	ndk	RF_1229	RF_0120	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.945
gmk	nrdA	RF_1229	RF_0709	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.920
gmk	nrdB	RF_1229	RF_0710	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.	0.905
gmk	rpoZ	RF_1229	RF_0944	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.972
gmk	spoT1	RF_1229	RF_0450	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog.	0.903
gmk	spoT15	RF_1229	RF_0384	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog.	0.934
gmk	spoT3	RF_1229	RF_0953	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog.	0.903
gmk	spoT7	RF_1229	RF_0438	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog.	0.903
gmk	spoT8	RF_1229	RF_0440	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog.	0.903
gmk	spoT9	RF_1229	RF_0884	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog.	0.903
ndk	gmk	RF_0120	RF_1229	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.945
ndk	nrdA	RF_0120	RF_0709	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.927
ndk	nrdB	RF_0120	RF_0710	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.	0.923
ndk	spoT1	RF_0120	RF_0450	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog.	0.900
ndk	spoT15	RF_0120	RF_0384	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog.	0.900
ndk	spoT3	RF_0120	RF_0953	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog.	0.900
ndk	spoT7	RF_0120	RF_0438	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog.	0.900
ndk	spoT8	RF_0120	RF_0440	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog.	0.900
ndk	spoT9	RF_0120	RF_0884	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog.	0.900
nrdA	gmk	RF_0709	RF_1229	Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.920