| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RF_1277 | miaB | RF_1277 | RF_1278 | Predicted ATPase; AAA+ superfamily. | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.578 |
| RF_1277 | mrcA | RF_1277 | RF_1276 | Predicted ATPase; AAA+ superfamily. | Penicillin-binding protein 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.741 |
| dacF | ftsW | RF_0609 | RF_0635 | Penicillin-binding protein DacF precursor; Belongs to the peptidase S11 family. | Cell division protein FtsW; Belongs to the SEDS family. | 0.427 |
| dacF | mrcA | RF_0609 | RF_1276 | Penicillin-binding protein DacF precursor; Belongs to the peptidase S11 family. | Penicillin-binding protein 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.942 |
| dacF | pbpA1 | RF_0609 | RF_0900 | Penicillin-binding protein DacF precursor; Belongs to the peptidase S11 family. | Penicillin-binding protein. | 0.941 |
| dacF | pbpA2 | RF_0609 | RF_0902 | Penicillin-binding protein DacF precursor; Belongs to the peptidase S11 family. | Penicillin-binding protein. | 0.953 |
| dacF | pbpC | RF_0609 | RF_1069 | Penicillin-binding protein DacF precursor; Belongs to the peptidase S11 family. | Bifunctional penicillin-binding protein 1C. | 0.900 |
| dacF | rlpA | RF_0609 | RF_0611 | Penicillin-binding protein DacF precursor; Belongs to the peptidase S11 family. | Rare lipoprotein A precursor; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.682 |
| ftsW | dacF | RF_0635 | RF_0609 | Cell division protein FtsW; Belongs to the SEDS family. | Penicillin-binding protein DacF precursor; Belongs to the peptidase S11 family. | 0.427 |
| ftsW | mrcA | RF_0635 | RF_1276 | Cell division protein FtsW; Belongs to the SEDS family. | Penicillin-binding protein 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.595 |
| ftsW | murC | RF_0635 | RF_1037 | Cell division protein FtsW; Belongs to the SEDS family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.971 |
| ftsW | pbpA1 | RF_0635 | RF_0900 | Cell division protein FtsW; Belongs to the SEDS family. | Penicillin-binding protein. | 0.925 |
| ftsW | pbpA2 | RF_0635 | RF_0902 | Cell division protein FtsW; Belongs to the SEDS family. | Penicillin-binding protein. | 0.985 |
| ftsW | rlpA | RF_0635 | RF_0611 | Cell division protein FtsW; Belongs to the SEDS family. | Rare lipoprotein A precursor; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.822 |
| miaB | RF_1277 | RF_1278 | RF_1277 | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | Predicted ATPase; AAA+ superfamily. | 0.578 |
| miaB | mrcA | RF_1278 | RF_1276 | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | Penicillin-binding protein 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.701 |
| mltG | mrcA | RF_0521 | RF_1276 | Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. | Penicillin-binding protein 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.627 |
| mltG | rlpA | RF_0521 | RF_0611 | Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. | Rare lipoprotein A precursor; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.702 |
| mrcA | RF_1277 | RF_1276 | RF_1277 | Penicillin-binding protein 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Predicted ATPase; AAA+ superfamily. | 0.741 |
| mrcA | dacF | RF_1276 | RF_0609 | Penicillin-binding protein 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Penicillin-binding protein DacF precursor; Belongs to the peptidase S11 family. | 0.942 |
