Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glnQGlutamine ABC transporter ATP-binding protein. (240 aa)    
Predicted Functional Partners:
yqiY
Amino acid ABC transporter permease protein; Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
 
 0.996
yqiX
Amino acid ABC transporter substrate binding protein.
 
 
 0.931
atm1
Multidrug resistance protein Atm1.
     
0.868
phnP
Metal-dependent hydrolases of the beta-lactamase superfamily I.
  
    0.860
glnA
Glutamine synthetase.
   
  
 0.704
acnA
Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein.
  
  
 0.634
polA
DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.609
RF_1372
Unknown.
  
    0.588
RF_1369
Antitoxin of toxin-antitoxin system StbD; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.576
pdhB
Pyruvate dehydrogenase E1 component, beta subunit precursor; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
      
 0.553
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
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