STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phnPMetal-dependent hydrolases of the beta-lactamase superfamily I. (254 aa)    
Predicted Functional Partners:
glnQ
Glutamine ABC transporter ATP-binding protein.
  
    0.860
lipB
Probable lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
 
    
 0.725
polA
DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.622
rlpA
Rare lipoprotein A precursor; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
       0.609
manC
Mannose-1-phosphate guanylyltransferase.
     
 0.586
RF_1372
Unknown.
       0.586
RF_1369
Antitoxin of toxin-antitoxin system StbD; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.576
queF
Unknown; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
      
 0.568
RF_0036
Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C.
  
  
 0.564
dinJ
DNA-damage-inducible protein J.
       0.471
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.