Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ampDAmpD protein homolog. (248 aa)    
Predicted Functional Partners:
mccF2
Microcin C7 resistance protein.
  
   
 0.714
mccF
Microcin C7 self-immunity protein.
  
   
 0.713
acrF
Hydrophobe/amphiphile efflux-1 HAE1 family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  
 0.628
RF_0570
Phage uncharacterized protein; Terminase large subunit.
       0.567
RF_0749
Phage prohead protease (HK97 family) and phage major capsid protein (HK97 family).
       0.566
blaD
Beta-lactamase Class D.
      
 0.536
pbpA2
Penicillin-binding protein.
 
   
 0.516
RF_0203
Beta-glucosidase.
 
   
 0.514
kefB
Glutathione-regulated potassium-efflux system protein KefB; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
       0.495
RF_1382
Uncharacterized conserved protein.
       0.476
Your Current Organism:
Rickettsia felis
NCBI taxonomy Id: 315456
Other names: R. felis URRWXCal2, Rickettsia felis URRWXCal2, Rickettsia felis str. URRWXCal2, Rickettsia felis strain URRWXCal2
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