STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABS24143.1Signal transduction histidine kinase, LytS; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; KEGG: baa:BA_0550 histidine kinase-like ATPases. (591 aa)    
Predicted Functional Partners:
ABS24142.1
Two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region; KEGG: baa:BA_0549 response regulator receiver domain.
 
 0.997
ABS24114.1
Two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region; KEGG: btl:BALH_4920 response regulator.
 
 
 0.910
ABS24141.1
PFAM: LrgA family protein; KEGG: btk:BT9727_5121 membrane protein; possible murein hydrolase exporter.
 
   
 0.763
lrgB
LrgB family protein; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily.
 
   
 0.650
ABS23994.1
PFAM: ABC transporter related; LytTr DNA-binding region; KEGG: btk:BT9727_4967 ABC transporter, ATP-binding protein and transcriptional regulator, LytTr DNA-binding domain fusion protein.
  
 
 0.563
Your Current Organism:
Bacillus cytotoxicus
NCBI taxonomy Id: 315749
Other names: B. cytotoxicus NVH 391-98, Bacillus cereus NVH 391-98, Bacillus cereus subsp. cytotoxicus NVH 391-98, Bacillus cereus subsp. cytotoxis NVH 391-98, Bacillus cytotoxicus NVH 391-98, Bacillus cytotoxicus str. NVH 391-98, Bacillus cytotoxicus strain NVH 391-98, Bacillus cytotoxis NVH 391-98
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