| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_0218 | RPE_2685 | RPE_0218 | RPE_2685 | PFAM: PfkB domain protein; KEGG: rpd:RPD_0251 PfkB. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | 0.576 |
| RPE_0218 | RPE_3275 | RPE_0218 | RPE_3275 | PFAM: PfkB domain protein; KEGG: rpd:RPD_0251 PfkB. | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)))/Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rpb:RPB_2497 bifunctional oxaloacetate decarboxylating malate dehydrogenase (NADP+)/phosphate acetyltransferase. | 0.538 |
| RPE_0218 | RPE_3692 | RPE_0218 | RPE_3692 | PFAM: PfkB domain protein; KEGG: rpd:RPD_0251 PfkB. | PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: rpc:RPC_4481 iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.556 |
| RPE_0218 | acpP | RPE_0218 | RPE_3305 | PFAM: PfkB domain protein; KEGG: rpd:RPD_0251 PfkB. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.514 |
| RPE_0218 | ahcY | RPE_0218 | RPE_4203 | PFAM: PfkB domain protein; KEGG: rpd:RPD_0251 PfkB. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.514 |
| RPE_0218 | gpt | RPE_0218 | RPE_2299 | PFAM: PfkB domain protein; KEGG: rpd:RPD_0251 PfkB. | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.566 |
| RPE_0218 | hisA | RPE_0218 | RPE_0367 | PFAM: PfkB domain protein; KEGG: rpd:RPD_0251 PfkB. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis; KEGG: rpc:RPC_0307 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. | 0.791 |
| RPE_0218 | murJ | RPE_0218 | RPE_0217 | PFAM: PfkB domain protein; KEGG: rpd:RPD_0251 PfkB. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.601 |
| RPE_0218 | purA | RPE_0218 | RPE_4141 | PFAM: PfkB domain protein; KEGG: rpd:RPD_0251 PfkB. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.564 |
| RPE_0218 | tal | RPE_0218 | RPE_3708 | PFAM: PfkB domain protein; KEGG: rpd:RPD_0251 PfkB. | Glucose-6-phosphate isomerase / transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. | 0.538 |
| RPE_2685 | RPE_0218 | RPE_2685 | RPE_0218 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | PFAM: PfkB domain protein; KEGG: rpd:RPD_0251 PfkB. | 0.576 |
| RPE_2685 | RPE_3275 | RPE_2685 | RPE_3275 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)))/Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rpb:RPB_2497 bifunctional oxaloacetate decarboxylating malate dehydrogenase (NADP+)/phosphate acetyltransferase. | 0.561 |
| RPE_2685 | RPE_3692 | RPE_2685 | RPE_3692 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: rpc:RPC_4481 iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.537 |
| RPE_2685 | tal | RPE_2685 | RPE_3708 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Glucose-6-phosphate isomerase / transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. | 0.995 |
| RPE_3275 | RPE_0218 | RPE_3275 | RPE_0218 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)))/Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rpb:RPB_2497 bifunctional oxaloacetate decarboxylating malate dehydrogenase (NADP+)/phosphate acetyltransferase. | PFAM: PfkB domain protein; KEGG: rpd:RPD_0251 PfkB. | 0.538 |
| RPE_3275 | RPE_2685 | RPE_3275 | RPE_2685 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)))/Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rpb:RPB_2497 bifunctional oxaloacetate decarboxylating malate dehydrogenase (NADP+)/phosphate acetyltransferase. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | 0.561 |
| RPE_3275 | RPE_3692 | RPE_3275 | RPE_3692 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)))/Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rpb:RPB_2497 bifunctional oxaloacetate decarboxylating malate dehydrogenase (NADP+)/phosphate acetyltransferase. | PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: rpc:RPC_4481 iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.726 |
| RPE_3275 | acpP | RPE_3275 | RPE_3305 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)))/Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rpb:RPB_2497 bifunctional oxaloacetate decarboxylating malate dehydrogenase (NADP+)/phosphate acetyltransferase. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.499 |
| RPE_3275 | tal | RPE_3275 | RPE_3708 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)))/Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rpb:RPB_2497 bifunctional oxaloacetate decarboxylating malate dehydrogenase (NADP+)/phosphate acetyltransferase. | Glucose-6-phosphate isomerase / transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. | 0.963 |
| RPE_3692 | RPE_0218 | RPE_3692 | RPE_0218 | PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: rpc:RPC_4481 iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | PFAM: PfkB domain protein; KEGG: rpd:RPD_0251 PfkB. | 0.556 |