| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_0601 | RPE_0602 | RPE_0601 | RPE_0602 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: rpd:RPD_1531 pyruvate/2-ketoisovalerate 2-oxoacid:acceptor oxidoreductase, beta subunit. | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 0.999 |
| RPE_0601 | RPE_0766 | RPE_0601 | RPE_0766 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: rpd:RPD_1531 pyruvate/2-ketoisovalerate 2-oxoacid:acceptor oxidoreductase, beta subunit. | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpc:RPC_0704 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 0.999 |
| RPE_0601 | RPE_0982 | RPE_0601 | RPE_0982 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: rpd:RPD_1531 pyruvate/2-ketoisovalerate 2-oxoacid:acceptor oxidoreductase, beta subunit. | 2-oxoglutarate ferredoxin oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: rpc:RPC_0697 pyruvate ferredoxin/flavodoxin oxidoreductase. | 0.997 |
| RPE_0601 | RPE_0984 | RPE_0601 | RPE_0984 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: rpd:RPD_1531 pyruvate/2-ketoisovalerate 2-oxoacid:acceptor oxidoreductase, beta subunit. | 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpc:RPC_0695 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 0.999 |
| RPE_0601 | RPE_0985 | RPE_0601 | RPE_0985 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: rpd:RPD_1531 pyruvate/2-ketoisovalerate 2-oxoacid:acceptor oxidoreductase, beta subunit. | Indolepyruvate ferredoxin oxidoreductase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: rpc:RPC_0694 pyruvate ferredoxin/flavodoxin oxidoreductase. | 0.964 |
| RPE_0601 | RPE_2614 | RPE_0601 | RPE_2614 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: rpd:RPD_1531 pyruvate/2-ketoisovalerate 2-oxoacid:acceptor oxidoreductase, beta subunit. | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.933 |
| RPE_0601 | RPE_3275 | RPE_0601 | RPE_3275 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: rpd:RPD_1531 pyruvate/2-ketoisovalerate 2-oxoacid:acceptor oxidoreductase, beta subunit. | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)))/Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rpb:RPB_2497 bifunctional oxaloacetate decarboxylating malate dehydrogenase (NADP+)/phosphate acetyltransferase. | 0.948 |
| RPE_0601 | RPE_3692 | RPE_0601 | RPE_3692 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: rpd:RPD_1531 pyruvate/2-ketoisovalerate 2-oxoacid:acceptor oxidoreductase, beta subunit. | PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: rpc:RPC_4481 iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.931 |
| RPE_0601 | RPE_3863 | RPE_0601 | RPE_3863 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: rpd:RPD_1531 pyruvate/2-ketoisovalerate 2-oxoacid:acceptor oxidoreductase, beta subunit. | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.947 |
| RPE_0601 | sucD | RPE_0601 | RPE_0298 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: rpd:RPD_1531 pyruvate/2-ketoisovalerate 2-oxoacid:acceptor oxidoreductase, beta subunit. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.927 |
| RPE_0602 | RPE_0601 | RPE_0602 | RPE_0601 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: rpd:RPD_1531 pyruvate/2-ketoisovalerate 2-oxoacid:acceptor oxidoreductase, beta subunit. | 0.999 |
| RPE_0602 | RPE_0766 | RPE_0602 | RPE_0766 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpc:RPC_0704 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 0.999 |
| RPE_0602 | RPE_0982 | RPE_0602 | RPE_0982 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 2-oxoglutarate ferredoxin oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: rpc:RPC_0697 pyruvate ferredoxin/flavodoxin oxidoreductase. | 0.984 |
| RPE_0602 | RPE_0984 | RPE_0602 | RPE_0984 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpc:RPC_0695 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 0.970 |
| RPE_0602 | RPE_0985 | RPE_0602 | RPE_0985 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | Indolepyruvate ferredoxin oxidoreductase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: rpc:RPC_0694 pyruvate ferredoxin/flavodoxin oxidoreductase. | 0.972 |
| RPE_0602 | RPE_2614 | RPE_0602 | RPE_2614 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.941 |
| RPE_0602 | RPE_3275 | RPE_0602 | RPE_3275 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)))/Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rpb:RPB_2497 bifunctional oxaloacetate decarboxylating malate dehydrogenase (NADP+)/phosphate acetyltransferase. | 0.956 |
| RPE_0602 | RPE_3692 | RPE_0602 | RPE_3692 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: rpc:RPC_4481 iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.950 |
| RPE_0602 | RPE_3863 | RPE_0602 | RPE_3863 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.954 |
| RPE_0602 | sucD | RPE_0602 | RPE_0298 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.945 |