STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (448 aa)    
Predicted Functional Partners:
RPE_0913
Fumarylacetoacetate hydrolase; KEGG: rpb:RPB_0909 fumarylacetoacetase; TIGRFAM: fumarylacetoacetase; PFAM: fumarylacetoacetate (FAA) hydrolase.
 
  
 0.990
RPE_0911
PFAM: beta-lactamase domain protein; KEGG: rpa:RPA4673 putative beta lactamase precursor.
 
   
 0.890
RPE_1446
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: rpa:RPA3992 fumarylacetoacetate (FAA) hydrolase.
  
  
 0.786
RPE_0909
PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: rpc:RPC_0888 monooxygenase, FAD-binding.
 
  
 0.782
RPE_1953
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: rpd:RPD_2022 5-carboxymethyl-2-hydroxymuconate delta-isomerase.
  
  
 0.774
RPE_4326
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: rpb:RPB_4234 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase.
  
  
 0.774
RPE_1797
KEGG: rpd:RPD_1882 hypothetical protein.
  
  
 0.763
RPE_2708
PFAM: transcriptional coactivator/pterin dehydratase; KEGG: rpc:RPC_2524 transcriptional coactivator/pterin dehydratase.
 
  
 0.756
RPE_0910
KEGG: rpb:RPB_0904 hypothetical protein.
 
     0.683
RPE_0897
PFAM: aminotransferase, class V; KEGG: rpc:RPC_4689 aminotransferase, class V.
   
  
 0.483
Your Current Organism:
Rhodopseudomonas palustris BisA53
NCBI taxonomy Id: 316055
Other names: R. palustris BisA53, Rhodopseudomonas palustris str. BisA53, Rhodopseudomonas palustris strain BisA53
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.