| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_0945 | queE | RPE_0945 | RPE_0946 | KEGG: rpc:RPC_0921 hypothetical protein. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.529 |
| RPE_0945 | trmL | RPE_0945 | RPE_0947 | KEGG: rpc:RPC_0921 hypothetical protein. | tRNA/rRNA methyltransferase (SpoU); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.562 |
| RPE_0948 | queE | RPE_0948 | RPE_0946 | Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.542 |
| RPE_0948 | trmL | RPE_0948 | RPE_0947 | Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | tRNA/rRNA methyltransferase (SpoU); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.519 |
| RPE_3176 | folE | RPE_3176 | RPE_0796 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: rpc:RPC_3517 ribonucleoside-triphosphate reductase, anaerobic. | PFAM: GTP cyclohydrolase I; KEGG: mag:amb4223 GTP cyclohydrolase I. | 0.802 |
| RPE_3176 | folE-2 | RPE_3176 | RPE_2348 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: rpc:RPC_3517 ribonucleoside-triphosphate reductase, anaerobic. | PFAM: GTP cyclohydrolase I; KEGG: rpc:RPC_3114 GTP cyclohydrolase I. | 0.802 |
| RPE_3176 | queE | RPE_3176 | RPE_0946 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: rpc:RPC_3517 ribonucleoside-triphosphate reductase, anaerobic. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.948 |
| RPE_3943 | folE | RPE_3943 | RPE_0796 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: rpc:RPC_3820 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | PFAM: GTP cyclohydrolase I; KEGG: mag:amb4223 GTP cyclohydrolase I. | 0.979 |
| RPE_3943 | folE-2 | RPE_3943 | RPE_2348 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: rpc:RPC_3820 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | PFAM: GTP cyclohydrolase I; KEGG: rpc:RPC_3114 GTP cyclohydrolase I. | 0.979 |
| RPE_3943 | queC | RPE_3943 | RPE_2884 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: rpc:RPC_3820 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.967 |
| RPE_3943 | queE | RPE_3943 | RPE_0946 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: rpc:RPC_3820 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.996 |
| RPE_3943 | queF | RPE_3943 | RPE_2606 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: rpc:RPC_3820 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.927 |
| folE | RPE_3176 | RPE_0796 | RPE_3176 | PFAM: GTP cyclohydrolase I; KEGG: mag:amb4223 GTP cyclohydrolase I. | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: rpc:RPC_3517 ribonucleoside-triphosphate reductase, anaerobic. | 0.802 |
| folE | RPE_3943 | RPE_0796 | RPE_3943 | PFAM: GTP cyclohydrolase I; KEGG: mag:amb4223 GTP cyclohydrolase I. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: rpc:RPC_3820 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | 0.979 |
| folE | folE-2 | RPE_0796 | RPE_2348 | PFAM: GTP cyclohydrolase I; KEGG: mag:amb4223 GTP cyclohydrolase I. | PFAM: GTP cyclohydrolase I; KEGG: rpc:RPC_3114 GTP cyclohydrolase I. | 0.905 |
| folE | queE | RPE_0796 | RPE_0946 | PFAM: GTP cyclohydrolase I; KEGG: mag:amb4223 GTP cyclohydrolase I. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.522 |
| folE-2 | RPE_3176 | RPE_2348 | RPE_3176 | PFAM: GTP cyclohydrolase I; KEGG: rpc:RPC_3114 GTP cyclohydrolase I. | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: rpc:RPC_3517 ribonucleoside-triphosphate reductase, anaerobic. | 0.802 |
| folE-2 | RPE_3943 | RPE_2348 | RPE_3943 | PFAM: GTP cyclohydrolase I; KEGG: rpc:RPC_3114 GTP cyclohydrolase I. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: rpc:RPC_3820 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | 0.979 |
| folE-2 | folE | RPE_2348 | RPE_0796 | PFAM: GTP cyclohydrolase I; KEGG: rpc:RPC_3114 GTP cyclohydrolase I. | PFAM: GTP cyclohydrolase I; KEGG: mag:amb4223 GTP cyclohydrolase I. | 0.905 |
| folE-2 | queE | RPE_2348 | RPE_0946 | PFAM: GTP cyclohydrolase I; KEGG: rpc:RPC_3114 GTP cyclohydrolase I. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.522 |