STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
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[Homology]
Score
RPE_19793-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: rpa:RPA1973 3-hydroxyisobutyrate dehydrogenase. (289 aa)    
Predicted Functional Partners:
RPE_2382
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: rpc:RPC_3095 methylmalonate-semialdehyde dehydrogenase.
 
 
 0.944
RPE_0674
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: rpb:RPB_4604 3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.933
RPE_2260
PFAM: aldehyde dehydrogenase; KEGG: rpd:RPD_2215 aldehyde dehydrogenase.
 
 
 0.932
RPE_2387
TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: rpa:RPA3446 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
  
  
 
0.922
RPE_0915
PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.902
RPE_3439
Carbamoyl-phosphate synthase L chain, ATP-binding protein; PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp; KEGG: rpc:RPC_3352 carbamoyl-phosphate synthase L chain, ATP-binding.
  
 
  0.825
RPE_4399
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rpd:RPD_1230 alcohol dehydrogenase, zinc-binding.
  
  
  0.822
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
  0.813
RPE_2388
PFAM: AMP-dependent synthetase and ligase; KEGG: rpa:RPA3445 probable acetyl-CoA synthetase.
  
 
  0.813
RPE_4455
PFAM: AMP-dependent synthetase and ligase; KEGG: rpc:RPC_4396 AMP-dependent synthetase and ligase.
  
 
  0.813
Your Current Organism:
Rhodopseudomonas palustris BisA53
NCBI taxonomy Id: 316055
Other names: R. palustris BisA53, Rhodopseudomonas palustris str. BisA53, Rhodopseudomonas palustris strain BisA53
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