STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPE_1989NADPH-glutathione reductase; Maintains high levels of reduced glutathione. (461 aa)    
Predicted Functional Partners:
RPE_2614
Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.999
pdhA
Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 
 0.950
gshB
KEGG: rpa:RPA0322 glutathione synthetase; TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase, ATP-binding; RimK domain protein ATP-grasp; Belongs to the prokaryotic GSH synthase family.
  
  
 0.944
RPE_2616
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.939
RPE_0410
PFAM: Thioredoxin domain; KEGG: rpa:RPA0267 possible thioredoxin.
  
 
 0.937
RPE_0254
PFAM: Glutathione S-transferase, N-terminal domain; KEGG: nha:Nham_0039 glutathione S-transferase-like.
  
 0.936
RPE_1706
Redoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
 
  
 0.936
RPE_4177
PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: rpc:RPC_4124 glutathione S-transferase-like; Belongs to the GST superfamily.
  
 0.936
RPE_3417
PFAM: Glutathione S-transferase, N-terminal domain; KEGG: rpc:RPC_3336 glutathione S-transferase-like.
  
 0.935
RPE_4164
PFAM: Glutathione S-transferase, N-terminal domain; KEGG: rpa:RPA4314 possible glutathione S-transferase; Belongs to the GST superfamily.
  
 0.935
Your Current Organism:
Rhodopseudomonas palustris BisA53
NCBI taxonomy Id: 316055
Other names: R. palustris BisA53, Rhodopseudomonas palustris str. BisA53, Rhodopseudomonas palustris strain BisA53
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