| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_2106 | ddl | RPE_2106 | RPE_2113 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: rpc:RPC_3307 cell cycle protein; Belongs to the SEDS family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.943 |
| RPE_2106 | ftsA | RPE_2106 | RPE_2115 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: rpc:RPC_3307 cell cycle protein; Belongs to the SEDS family. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.911 |
| RPE_2106 | ftsQ | RPE_2106 | RPE_2114 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: rpc:RPC_3307 cell cycle protein; Belongs to the SEDS family. | Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | 0.986 |
| RPE_2106 | mraY | RPE_2106 | RPE_2104 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: rpc:RPC_3307 cell cycle protein; Belongs to the SEDS family. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.972 |
| RPE_2106 | murB | RPE_2106 | RPE_2110 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: rpc:RPC_3307 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.751 |
| RPE_2106 | murC | RPE_2106 | RPE_2108 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: rpc:RPC_3307 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.985 |
| RPE_2106 | murD | RPE_2106 | RPE_2105 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: rpc:RPC_3307 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.964 |
| RPE_2106 | murE | RPE_2106 | RPE_2102 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: rpc:RPC_3307 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.884 |
| RPE_2106 | murF | RPE_2106 | RPE_2103 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: rpc:RPC_3307 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.938 |
| RPE_2106 | murG | RPE_2106 | RPE_2107 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: rpc:RPC_3307 cell cycle protein; Belongs to the SEDS family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.992 |
| ddl | RPE_2106 | RPE_2113 | RPE_2106 | D-alanine--D-alanine ligase; Cell wall formation. | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: rpc:RPC_3307 cell cycle protein; Belongs to the SEDS family. | 0.943 |
| ddl | ftsA | RPE_2113 | RPE_2115 | D-alanine--D-alanine ligase; Cell wall formation. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.985 |
| ddl | ftsQ | RPE_2113 | RPE_2114 | D-alanine--D-alanine ligase; Cell wall formation. | Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | 0.988 |
| ddl | mraY | RPE_2113 | RPE_2104 | D-alanine--D-alanine ligase; Cell wall formation. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.918 |
| ddl | murB | RPE_2113 | RPE_2110 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.959 |
| ddl | murC | RPE_2113 | RPE_2108 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.991 |
| ddl | murD | RPE_2113 | RPE_2105 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.957 |
| ddl | murE | RPE_2113 | RPE_2102 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.904 |
| ddl | murF | RPE_2113 | RPE_2103 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.996 |
| ddl | murG | RPE_2113 | RPE_2107 | D-alanine--D-alanine ligase; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.962 |