| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_0002 | RPE_2169 | RPE_0002 | RPE_2169 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: ava:Ava_B0306 hypothetical protein. | 0.833 |
| RPE_0002 | RPE_3249 | RPE_0002 | RPE_3249 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: aba:Acid345_4269 hypothetical protein. | 0.667 |
| RPE_0002 | RPE_4912 | RPE_0002 | RPE_4912 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; KEGG: rpd:RPD_4412 ATP-dependent DNA helicase RecQ. | 0.854 |
| RPE_0002 | mutS | RPE_0002 | RPE_0246 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.982 |
| RPE_0002 | polA | RPE_0002 | RPE_4821 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.997 |
| RPE_0002 | recA | RPE_0002 | RPE_1594 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.929 |
| RPE_2169 | RPE_0002 | RPE_2169 | RPE_0002 | KEGG: ava:Ava_B0306 hypothetical protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.833 |
| RPE_2169 | RPE_3249 | RPE_2169 | RPE_3249 | KEGG: ava:Ava_B0306 hypothetical protein. | KEGG: aba:Acid345_4269 hypothetical protein. | 0.790 |
| RPE_2169 | RPE_3250 | RPE_2169 | RPE_3250 | KEGG: ava:Ava_B0306 hypothetical protein. | KEGG: oih:OB0176 hypothetical protein. | 0.783 |
| RPE_2169 | RPE_3251 | RPE_2169 | RPE_3251 | KEGG: ava:Ava_B0306 hypothetical protein. | Endonuclease; KEGG: eba:ebA6352 endonuclease. | 0.801 |
| RPE_2169 | RPE_3253 | RPE_2169 | RPE_3253 | KEGG: ava:Ava_B0306 hypothetical protein. | T/G mismatch-specific endonuclease; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination. | 0.738 |
| RPE_2169 | RPE_3254 | RPE_2169 | RPE_3254 | KEGG: ava:Ava_B0306 hypothetical protein. | KEGG: aba:Acid345_4264 DNA-cytosine methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.786 |
| RPE_2169 | RPE_4912 | RPE_2169 | RPE_4912 | KEGG: ava:Ava_B0306 hypothetical protein. | TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; KEGG: rpd:RPD_4412 ATP-dependent DNA helicase RecQ. | 0.797 |
| RPE_2169 | mutS | RPE_2169 | RPE_0246 | KEGG: ava:Ava_B0306 hypothetical protein. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.985 |
| RPE_2169 | polA | RPE_2169 | RPE_4821 | KEGG: ava:Ava_B0306 hypothetical protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.910 |
| RPE_2169 | recA | RPE_2169 | RPE_1594 | KEGG: ava:Ava_B0306 hypothetical protein. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.593 |
| RPE_3249 | RPE_0002 | RPE_3249 | RPE_0002 | KEGG: aba:Acid345_4269 hypothetical protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.667 |
| RPE_3249 | RPE_2169 | RPE_3249 | RPE_2169 | KEGG: aba:Acid345_4269 hypothetical protein. | KEGG: ava:Ava_B0306 hypothetical protein. | 0.790 |
| RPE_3249 | RPE_3250 | RPE_3249 | RPE_3250 | KEGG: aba:Acid345_4269 hypothetical protein. | KEGG: oih:OB0176 hypothetical protein. | 0.955 |
| RPE_3249 | RPE_3251 | RPE_3249 | RPE_3251 | KEGG: aba:Acid345_4269 hypothetical protein. | Endonuclease; KEGG: eba:ebA6352 endonuclease. | 0.960 |