node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPE_2219 | RPE_2220 | RPE_2219 | RPE_2220 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | 0.999 |
RPE_2219 | RPE_2221 | RPE_2219 | RPE_2221 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | 0.999 |
RPE_2219 | RPE_2222 | RPE_2219 | RPE_2222 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | 0.992 |
RPE_2219 | RPE_2223 | RPE_2219 | RPE_2223 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rpc:RPC_1886 precorrin-3B C17-methyltransferase. | 0.999 |
RPE_2219 | RPE_2224 | RPE_2219 | RPE_2224 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rpc:RPC_1887 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.978 |
RPE_2219 | RPE_2225 | RPE_2219 | RPE_2225 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | 0.984 |
RPE_2219 | RPE_2230 | RPE_2219 | RPE_2230 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | 0.996 |
RPE_2219 | cobB | RPE_2219 | RPE_2218 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.986 |
RPE_2219 | cobQ | RPE_2219 | RPE_2238 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.956 |
RPE_2219 | cobQ-2 | RPE_2219 | RPE_3122 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.958 |
RPE_2220 | RPE_2219 | RPE_2220 | RPE_2219 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | 0.999 |
RPE_2220 | RPE_2221 | RPE_2220 | RPE_2221 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | 0.994 |
RPE_2220 | RPE_2222 | RPE_2220 | RPE_2222 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | 0.979 |
RPE_2220 | RPE_2223 | RPE_2220 | RPE_2223 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rpc:RPC_1886 precorrin-3B C17-methyltransferase. | 0.957 |
RPE_2220 | RPE_2224 | RPE_2220 | RPE_2224 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rpc:RPC_1887 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.950 |
RPE_2220 | RPE_2225 | RPE_2220 | RPE_2225 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | 0.939 |
RPE_2220 | RPE_2230 | RPE_2220 | RPE_2230 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | 0.952 |
RPE_2220 | cobB | RPE_2220 | RPE_2218 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.967 |
RPE_2220 | cobQ | RPE_2220 | RPE_2238 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.624 |
RPE_2220 | cobQ-2 | RPE_2220 | RPE_3122 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.624 |