| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_2221 | RPE_2225 | RPE_2221 | RPE_2225 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | 0.999 |
| RPE_2221 | RPE_2231 | RPE_2221 | RPE_2231 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | KEGG: rru:Rru_A0458 hypothetical protein. | 0.603 |
| RPE_2221 | RPE_2232 | RPE_2221 | RPE_2232 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | KEGG: rpd:RPD_0641 Cob(II)yrinic acid a,c-diamide reductase; TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase. | 0.613 |
| RPE_2221 | RPE_2234 | RPE_2221 | RPE_2234 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.645 |
| RPE_2221 | RPE_2237 | RPE_2221 | RPE_2237 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.675 |
| RPE_2221 | RPE_2240 | RPE_2221 | RPE_2240 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | PFAM: aminotransferase, class I and II; KEGG: rpc:RPC_3743 aminotransferase, class I and II. | 0.570 |
| RPE_2221 | cobB | RPE_2221 | RPE_2218 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.985 |
| RPE_2221 | cobT | RPE_2221 | RPE_2229 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.523 |
| RPE_2221 | cobT-2 | RPE_2221 | RPE_3845 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.523 |
| RPE_2225 | RPE_2221 | RPE_2225 | RPE_2221 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | 0.999 |
| RPE_2225 | RPE_2231 | RPE_2225 | RPE_2231 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | KEGG: rru:Rru_A0458 hypothetical protein. | 0.431 |
| RPE_2225 | RPE_2232 | RPE_2225 | RPE_2232 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | KEGG: rpd:RPD_0641 Cob(II)yrinic acid a,c-diamide reductase; TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase. | 0.629 |
| RPE_2225 | RPE_2234 | RPE_2225 | RPE_2234 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.630 |
| RPE_2225 | RPE_2237 | RPE_2225 | RPE_2237 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.534 |
| RPE_2225 | RPE_2240 | RPE_2225 | RPE_2240 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | PFAM: aminotransferase, class I and II; KEGG: rpc:RPC_3743 aminotransferase, class I and II. | 0.454 |
| RPE_2225 | cobB | RPE_2225 | RPE_2218 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.995 |
| RPE_2225 | cobT | RPE_2225 | RPE_2229 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.611 |
| RPE_2225 | cobT-2 | RPE_2225 | RPE_3845 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.402 |
| RPE_2231 | RPE_2221 | RPE_2231 | RPE_2221 | KEGG: rru:Rru_A0458 hypothetical protein. | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | 0.603 |
| RPE_2231 | RPE_2225 | RPE_2231 | RPE_2225 | KEGG: rru:Rru_A0458 hypothetical protein. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | 0.431 |