| node1 | node2 | node1 annotation | node2 annotation | score |
| RPE_2220 | RPE_2221 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | 0.994 |
| RPE_2220 | RPE_2222 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | 0.979 |
| RPE_2220 | RPE_2224 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rpc:RPC_1887 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.950 |
| RPE_2220 | RPE_2225 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | 0.939 |
| RPE_2220 | RPE_2226 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | Hypothetical protein; KEGG: rpc:RPC_1889 cobaltochelatase, CobN subunit. | 0.823 |
| RPE_2220 | RPE_2233 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | PFAM: protein of unknown function DUF1636; KEGG: rpb:RPB_0741 protein of unknown function DUF1636. | 0.660 |
| RPE_2220 | RPE_2234 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.409 |
| RPE_2220 | RPE_2235 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | TIGRFAM: cobalamin biosynthesis protein CobW; PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein; KEGG: rpd:RPD_0637 cobalamin (vitamin B12) biosynthesis CobW. | 0.444 |
| RPE_2220 | RPE_3489 | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | KEGG: rpd:RPD_2477 hypothetical protein. | 0.414 |
| RPE_2221 | RPE_2220 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | 0.994 |
| RPE_2221 | RPE_2222 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | 0.999 |
| RPE_2221 | RPE_2224 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rpc:RPC_1887 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.985 |
| RPE_2221 | RPE_2225 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | 0.999 |
| RPE_2221 | RPE_2226 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | Hypothetical protein; KEGG: rpc:RPC_1889 cobaltochelatase, CobN subunit. | 0.862 |
| RPE_2221 | RPE_2233 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | PFAM: protein of unknown function DUF1636; KEGG: rpb:RPB_0741 protein of unknown function DUF1636. | 0.633 |
| RPE_2221 | RPE_2234 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.645 |
| RPE_2221 | RPE_2235 | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | TIGRFAM: cobalamin biosynthesis protein CobW; PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein; KEGG: rpd:RPD_0637 cobalamin (vitamin B12) biosynthesis CobW. | 0.648 |
| RPE_2222 | RPE_2220 | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | KEGG: rpa:RPA2085 cobalamin biosynthesis protein G; CbiG. | 0.979 |
| RPE_2222 | RPE_2221 | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | KEGG: rpb:RPB_3182 precorrin-6y C5,15-methyltransferase, subunit CbiE; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. | 0.999 |
| RPE_2222 | RPE_2224 | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rpc:RPC_1887 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.977 |