| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_2219 | RPE_2222 | RPE_2219 | RPE_2222 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | 0.992 |
| RPE_2219 | RPE_2223 | RPE_2219 | RPE_2223 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rpc:RPC_1886 precorrin-3B C17-methyltransferase. | 0.999 |
| RPE_2219 | RPE_2225 | RPE_2219 | RPE_2225 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | 0.984 |
| RPE_2219 | RPE_2234 | RPE_2219 | RPE_2234 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.846 |
| RPE_2219 | RPE_2237 | RPE_2219 | RPE_2237 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.506 |
| RPE_2219 | RPE_2240 | RPE_2219 | RPE_2240 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: aminotransferase, class I and II; KEGG: rpc:RPC_3743 aminotransferase, class I and II. | 0.445 |
| RPE_2219 | cobB | RPE_2219 | RPE_2218 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.986 |
| RPE_2219 | cobD | RPE_2219 | RPE_2239 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.823 |
| RPE_2219 | cobQ | RPE_2219 | RPE_2238 | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.956 |
| RPE_2222 | RPE_2219 | RPE_2222 | RPE_2219 | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | 0.992 |
| RPE_2222 | RPE_2223 | RPE_2222 | RPE_2223 | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rpc:RPC_1886 precorrin-3B C17-methyltransferase. | 0.985 |
| RPE_2222 | RPE_2225 | RPE_2222 | RPE_2225 | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | 0.981 |
| RPE_2222 | RPE_2234 | RPE_2222 | RPE_2234 | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.451 |
| RPE_2222 | RPE_2237 | RPE_2222 | RPE_2237 | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.401 |
| RPE_2222 | cobB | RPE_2222 | RPE_2218 | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.940 |
| RPE_2222 | cobD | RPE_2222 | RPE_2239 | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.634 |
| RPE_2222 | cobQ | RPE_2222 | RPE_2238 | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.917 |
| RPE_2223 | RPE_2219 | RPE_2223 | RPE_2219 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rpc:RPC_1886 precorrin-3B C17-methyltransferase. | KEGG: rpd:RPD_2314 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | 0.999 |
| RPE_2223 | RPE_2222 | RPE_2223 | RPE_2222 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rpc:RPC_1886 precorrin-3B C17-methyltransferase. | KEGG: rpc:RPC_1885 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK. | 0.985 |
| RPE_2223 | RPE_2225 | RPE_2223 | RPE_2225 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rpc:RPC_1886 precorrin-3B C17-methyltransferase. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rpa:RPA2090 precorrin isomerase CobH. | 0.999 |