| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_0897 | RPE_2185 | RPE_0897 | RPE_2185 | PFAM: aminotransferase, class V; KEGG: rpc:RPC_4689 aminotransferase, class V. | KEGG: rpb:RPB_3347 phosphoserine phosphatase SerB:HAD-superfamily hydrolase subfamily IB, PSPase-like; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | 0.933 |
| RPE_0897 | RPE_2312 | RPE_0897 | RPE_2312 | PFAM: aminotransferase, class V; KEGG: rpc:RPC_4689 aminotransferase, class V. | KEGG: rpc:RPC_3144 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein. | 0.839 |
| RPE_0897 | RPE_3185 | RPE_0897 | RPE_3185 | PFAM: aminotransferase, class V; KEGG: rpc:RPC_4689 aminotransferase, class V. | KEGG: rpd:RPD_3226 serine O-acetyltransferase. | 0.804 |
| RPE_0897 | glyA | RPE_0897 | RPE_2808 | PFAM: aminotransferase, class V; KEGG: rpc:RPC_4689 aminotransferase, class V. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.937 |
| RPE_0897 | trpA | RPE_0897 | RPE_0455 | PFAM: aminotransferase, class V; KEGG: rpc:RPC_4689 aminotransferase, class V. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.905 |
| RPE_2185 | RPE_0897 | RPE_2185 | RPE_0897 | KEGG: rpb:RPB_3347 phosphoserine phosphatase SerB:HAD-superfamily hydrolase subfamily IB, PSPase-like; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | PFAM: aminotransferase, class V; KEGG: rpc:RPC_4689 aminotransferase, class V. | 0.933 |
| RPE_2185 | RPE_2312 | RPE_2185 | RPE_2312 | KEGG: rpb:RPB_3347 phosphoserine phosphatase SerB:HAD-superfamily hydrolase subfamily IB, PSPase-like; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | KEGG: rpc:RPC_3144 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein. | 0.848 |
| RPE_2185 | RPE_3185 | RPE_2185 | RPE_3185 | KEGG: rpb:RPB_3347 phosphoserine phosphatase SerB:HAD-superfamily hydrolase subfamily IB, PSPase-like; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | KEGG: rpd:RPD_3226 serine O-acetyltransferase. | 0.848 |
| RPE_2185 | glyA | RPE_2185 | RPE_2808 | KEGG: rpb:RPB_3347 phosphoserine phosphatase SerB:HAD-superfamily hydrolase subfamily IB, PSPase-like; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.936 |
| RPE_2185 | trpA | RPE_2185 | RPE_0455 | KEGG: rpb:RPB_3347 phosphoserine phosphatase SerB:HAD-superfamily hydrolase subfamily IB, PSPase-like; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.905 |
| RPE_2312 | RPE_0897 | RPE_2312 | RPE_0897 | KEGG: rpc:RPC_3144 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein. | PFAM: aminotransferase, class V; KEGG: rpc:RPC_4689 aminotransferase, class V. | 0.839 |
| RPE_2312 | RPE_2185 | RPE_2312 | RPE_2185 | KEGG: rpc:RPC_3144 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein. | KEGG: rpb:RPB_3347 phosphoserine phosphatase SerB:HAD-superfamily hydrolase subfamily IB, PSPase-like; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | 0.848 |
| RPE_2312 | RPE_2734 | RPE_2312 | RPE_2734 | KEGG: rpc:RPC_3144 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein. | PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: rpb:RPB_2907 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | 0.987 |
| RPE_2312 | RPE_2774 | RPE_2312 | RPE_2774 | KEGG: rpc:RPC_3144 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein. | TIGRFAM: cysteine synthases; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: rpc:RPC_2594 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.994 |
| RPE_2312 | RPE_2937 | RPE_2312 | RPE_2937 | KEGG: rpc:RPC_3144 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein. | PFAM: dihydrodipicolinate reductase; homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; KEGG: rpc:RPC_2816 homoserine dehydrogenase. | 0.829 |
| RPE_2312 | RPE_3185 | RPE_2312 | RPE_3185 | KEGG: rpc:RPC_3144 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein. | KEGG: rpd:RPD_3226 serine O-acetyltransferase. | 0.923 |
| RPE_2312 | RPE_3624 | RPE_2312 | RPE_3624 | KEGG: rpc:RPC_3144 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein. | TIGRFAM: cysteine synthases; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: rpc:RPC_3639 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.994 |
| RPE_2312 | cysS | RPE_2312 | RPE_1998 | KEGG: rpc:RPC_3144 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein. | KEGG: rpd:RPD_2065 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: cysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.938 |
| RPE_2312 | glyA | RPE_2312 | RPE_2808 | KEGG: rpc:RPC_3144 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.835 |
| RPE_2312 | trpA | RPE_2312 | RPE_0455 | KEGG: rpc:RPC_3144 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.818 |