| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_0771 | RPE_2807 | RPE_0771 | RPE_2807 | PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: bja:blr6465 putative steroid monooxygenase. | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; glucose/ribitol dehydrogenase; KEGG: bja:blr1253 dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.496 |
| RPE_0771 | RPE_3674 | RPE_0771 | RPE_3674 | PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: bja:blr6465 putative steroid monooxygenase. | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; Insect alcohol dehydrogenase family; KEGG: bja:blr7343 probable short-chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.446 |
| RPE_2806 | RPE_2807 | RPE_2806 | RPE_2807 | KEGG: rpc:RPC_2657 hypothetical protein. | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; glucose/ribitol dehydrogenase; KEGG: bja:blr1253 dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.424 |
| RPE_2807 | RPE_0771 | RPE_2807 | RPE_0771 | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; glucose/ribitol dehydrogenase; KEGG: bja:blr1253 dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: bja:blr6465 putative steroid monooxygenase. | 0.496 |
| RPE_2807 | RPE_2806 | RPE_2807 | RPE_2806 | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; glucose/ribitol dehydrogenase; KEGG: bja:blr1253 dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | KEGG: rpc:RPC_2657 hypothetical protein. | 0.424 |
| RPE_2807 | RPE_2810 | RPE_2807 | RPE_2810 | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; glucose/ribitol dehydrogenase; KEGG: bja:blr1253 dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.426 |
| RPE_2807 | RPE_3674 | RPE_2807 | RPE_3674 | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; glucose/ribitol dehydrogenase; KEGG: bja:blr1253 dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; Insect alcohol dehydrogenase family; KEGG: bja:blr7343 probable short-chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.454 |
| RPE_2807 | RPE_4235 | RPE_2807 | RPE_4235 | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; glucose/ribitol dehydrogenase; KEGG: bja:blr1253 dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bja:blr5976 putative oxidoreductase. | 0.505 |
| RPE_2807 | glyA | RPE_2807 | RPE_2808 | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; glucose/ribitol dehydrogenase; KEGG: bja:blr1253 dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.422 |
| RPE_2810 | RPE_2807 | RPE_2810 | RPE_2807 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; glucose/ribitol dehydrogenase; KEGG: bja:blr1253 dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.426 |
| RPE_2810 | glyA | RPE_2810 | RPE_2808 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.575 |
| RPE_3674 | RPE_0771 | RPE_3674 | RPE_0771 | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; Insect alcohol dehydrogenase family; KEGG: bja:blr7343 probable short-chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: bja:blr6465 putative steroid monooxygenase. | 0.446 |
| RPE_3674 | RPE_2807 | RPE_3674 | RPE_2807 | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; Insect alcohol dehydrogenase family; KEGG: bja:blr7343 probable short-chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; glucose/ribitol dehydrogenase; KEGG: bja:blr1253 dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.454 |
| RPE_3674 | RPE_4235 | RPE_3674 | RPE_4235 | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; Insect alcohol dehydrogenase family; KEGG: bja:blr7343 probable short-chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bja:blr5976 putative oxidoreductase. | 0.487 |
| RPE_4235 | RPE_2807 | RPE_4235 | RPE_2807 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bja:blr5976 putative oxidoreductase. | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; glucose/ribitol dehydrogenase; KEGG: bja:blr1253 dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.505 |
| RPE_4235 | RPE_3674 | RPE_4235 | RPE_3674 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bja:blr5976 putative oxidoreductase. | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; Insect alcohol dehydrogenase family; KEGG: bja:blr7343 probable short-chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.487 |
| glyA | RPE_2807 | RPE_2808 | RPE_2807 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; glucose/ribitol dehydrogenase; KEGG: bja:blr1253 dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.422 |
| glyA | RPE_2810 | RPE_2808 | RPE_2810 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.575 |