| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_1410 | RPE_2810 | RPE_1410 | RPE_2810 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; KEGG: rpc:RPC_1399 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.786 |
| RPE_1410 | RPE_2811 | RPE_1410 | RPE_2811 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; KEGG: rpc:RPC_1399 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | PFAM: Lumazine-binding protein; KEGG: rpc:RPC_2662 riboflavin synthase, alpha subunit. | 0.949 |
| RPE_1410 | RPE_4357 | RPE_1410 | RPE_4357 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; KEGG: rpc:RPC_1399 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.580 |
| RPE_1410 | ribH | RPE_1410 | RPE_1429 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; KEGG: rpc:RPC_1399 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.942 |
| RPE_1410 | ribH-2 | RPE_1410 | RPE_2812 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; KEGG: rpc:RPC_1399 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.949 |
| RPE_1676 | RPE_2811 | RPE_1676 | RPE_2811 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rpc:RPC_1647 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | PFAM: Lumazine-binding protein; KEGG: rpc:RPC_2662 riboflavin synthase, alpha subunit. | 0.669 |
| RPE_1676 | rpmE | RPE_1676 | RPE_0665 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rpc:RPC_1647 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | LSU ribosomal protein L31P; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. | 0.669 |
| RPE_1676 | rpmJ | RPE_1676 | RPE_4115 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rpc:RPC_1647 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | TIGRFAM: ribosomal protein L36; KEGG: rpc:RPC_3989 ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. | 0.584 |
| RPE_2810 | RPE_1410 | RPE_2810 | RPE_1410 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; KEGG: rpc:RPC_1399 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.786 |
| RPE_2810 | RPE_2811 | RPE_2810 | RPE_2811 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | PFAM: Lumazine-binding protein; KEGG: rpc:RPC_2662 riboflavin synthase, alpha subunit. | 0.999 |
| RPE_2810 | RPE_4357 | RPE_2810 | RPE_4357 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.999 |
| RPE_2810 | nrdR | RPE_2810 | RPE_2809 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Ribonucleotide reductase regulator NrdR-like protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.944 |
| RPE_2810 | ribH | RPE_2810 | RPE_1429 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.960 |
| RPE_2810 | ribH-2 | RPE_2810 | RPE_2812 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.993 |
| RPE_2811 | RPE_1410 | RPE_2811 | RPE_1410 | PFAM: Lumazine-binding protein; KEGG: rpc:RPC_2662 riboflavin synthase, alpha subunit. | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; KEGG: rpc:RPC_1399 riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.949 |
| RPE_2811 | RPE_1676 | RPE_2811 | RPE_1676 | PFAM: Lumazine-binding protein; KEGG: rpc:RPC_2662 riboflavin synthase, alpha subunit. | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rpc:RPC_1647 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | 0.669 |
| RPE_2811 | RPE_2810 | RPE_2811 | RPE_2810 | PFAM: Lumazine-binding protein; KEGG: rpc:RPC_2662 riboflavin synthase, alpha subunit. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| RPE_2811 | RPE_3282 | RPE_2811 | RPE_3282 | PFAM: Lumazine-binding protein; KEGG: rpc:RPC_2662 riboflavin synthase, alpha subunit. | Regulatory inactivation of DnaA Hda protein; KEGG: rpc:RPC_2328 chromosomal replication initiator, DnaA; Belongs to the DnaA family. | 0.706 |
| RPE_2811 | RPE_4357 | RPE_2811 | RPE_4357 | PFAM: Lumazine-binding protein; KEGG: rpc:RPC_2662 riboflavin synthase, alpha subunit. | GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.998 |
| RPE_2811 | nrdR | RPE_2811 | RPE_2809 | PFAM: Lumazine-binding protein; KEGG: rpc:RPC_2662 riboflavin synthase, alpha subunit. | Ribonucleotide reductase regulator NrdR-like protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.842 |