| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_0464 | RPE_2693 | RPE_0464 | RPE_2693 | PFAM: aminoglycoside phosphotransferase; protein of unknown function UPF0079; KEGG: rpc:RPC_0383 protein of unknown function UPF0079. | Beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase, family 3 domain protein; KEGG: rpb:RPB_2748 beta-N-acetylhexosaminidase. | 0.929 |
| RPE_0464 | anmK | RPE_0464 | RPE_2971 | PFAM: aminoglycoside phosphotransferase; protein of unknown function UPF0079; KEGG: rpc:RPC_0383 protein of unknown function UPF0079. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.453 |
| RPE_2098 | RPE_2693 | RPE_2098 | RPE_2693 | PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase, family 2; KEGG: rpc:RPC_2185 negative regulator of AmpC, AmpD. | Beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase, family 3 domain protein; KEGG: rpb:RPB_2748 beta-N-acetylhexosaminidase. | 0.650 |
| RPE_2098 | anmK | RPE_2098 | RPE_2971 | PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase, family 2; KEGG: rpc:RPC_2185 negative regulator of AmpC, AmpD. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.487 |
| RPE_2693 | RPE_0464 | RPE_2693 | RPE_0464 | Beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase, family 3 domain protein; KEGG: rpb:RPB_2748 beta-N-acetylhexosaminidase. | PFAM: aminoglycoside phosphotransferase; protein of unknown function UPF0079; KEGG: rpc:RPC_0383 protein of unknown function UPF0079. | 0.929 |
| RPE_2693 | RPE_2098 | RPE_2693 | RPE_2098 | Beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase, family 3 domain protein; KEGG: rpb:RPB_2748 beta-N-acetylhexosaminidase. | PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase, family 2; KEGG: rpc:RPC_2185 negative regulator of AmpC, AmpD. | 0.650 |
| RPE_2693 | anmK | RPE_2693 | RPE_2971 | Beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase, family 3 domain protein; KEGG: rpb:RPB_2748 beta-N-acetylhexosaminidase. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.640 |
| RPE_2810 | anmK | RPE_2810 | RPE_2971 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.472 |
| anmK | RPE_0464 | RPE_2971 | RPE_0464 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | PFAM: aminoglycoside phosphotransferase; protein of unknown function UPF0079; KEGG: rpc:RPC_0383 protein of unknown function UPF0079. | 0.453 |
| anmK | RPE_2098 | RPE_2971 | RPE_2098 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase, family 2; KEGG: rpc:RPC_2185 negative regulator of AmpC, AmpD. | 0.487 |
| anmK | RPE_2693 | RPE_2971 | RPE_2693 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase, family 3 domain protein; KEGG: rpb:RPB_2748 beta-N-acetylhexosaminidase. | 0.640 |
| anmK | RPE_2810 | RPE_2971 | RPE_2810 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.472 |
| anmK | tyrS | RPE_2971 | RPE_2972 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.579 |
| tyrS | anmK | RPE_2972 | RPE_2971 | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.579 |