STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPE_2985PFAM: protein of unknown function DUF1236; KEGG: rpc:RPC_2866 protein of unknown function DUF1236. (228 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.697
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
   
 
 0.697
RPE_2950
KEGG: nha:Nham_2317 DNA topoisomerase IV, B subunit.
   
 
 0.697
RPE_3249
KEGG: aba:Acid345_4269 hypothetical protein.
   
 
 0.697
RPE_2671
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: bur:Bcep18194_B1067 TPR repeat protein.
  
  
 0.627
RPE_4240
TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: sco:SCO4880 transferase.
  
  
 0.573
RPE_0517
PFAM: OmpA/MotB domain protein; KEGG: rpc:RPC_0065 OmpA/MotB.
  
 
 0.442
RPE_0907
PFAM: OmpA/MotB domain protein; KEGG: rpb:RPB_0896 OmpA/MotB.
  
 
 0.442
RPE_1792
PFAM: OmpA/MotB domain protein; KEGG: rpb:RPB_3590 OmpA/MotB.
  
 
 0.442
pal
OmpA/MotB domain protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.442
Your Current Organism:
Rhodopseudomonas palustris BisA53
NCBI taxonomy Id: 316055
Other names: R. palustris BisA53, Rhodopseudomonas palustris str. BisA53, Rhodopseudomonas palustris strain BisA53
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