| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_0205 | era | RPE_0205 | RPE_3021 | PFAM: PhoH family protein; KH, type 1, domain protein; KEGG: rpc:RPC_0469 PhoH-like protein. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.653 |
| RPE_0205 | recO | RPE_0205 | RPE_3018 | PFAM: PhoH family protein; KH, type 1, domain protein; KEGG: rpc:RPC_0469 PhoH-like protein. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.887 |
| RPE_0460 | RPE_0503 | RPE_0460 | RPE_0503 | DNA helicase/exodeoxyribonuclease V, subunit A; PFAM: UvrD/REP helicase; KEGG: rpc:RPC_0387 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. | PFAM: Glutathione S-transferase, C-terminal domain; KEGG: rpc:RPC_0439 glutathione S-transferase-like. | 0.731 |
| RPE_0460 | RPE_3282 | RPE_0460 | RPE_3282 | DNA helicase/exodeoxyribonuclease V, subunit A; PFAM: UvrD/REP helicase; KEGG: rpc:RPC_0387 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. | Regulatory inactivation of DnaA Hda protein; KEGG: rpc:RPC_2328 chromosomal replication initiator, DnaA; Belongs to the DnaA family. | 0.524 |
| RPE_0460 | RPE_4131 | RPE_0460 | RPE_4131 | DNA helicase/exodeoxyribonuclease V, subunit A; PFAM: UvrD/REP helicase; KEGG: rpc:RPC_0387 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. | PFAM: protein of unknown function DUF1013; KEGG: rpa:RPA4272 hypothetical protein. | 0.681 |
| RPE_0460 | parC | RPE_0460 | RPE_3017 | DNA helicase/exodeoxyribonuclease V, subunit A; PFAM: UvrD/REP helicase; KEGG: rpc:RPC_0387 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.425 |
| RPE_0460 | recF | RPE_0460 | RPE_0003 | DNA helicase/exodeoxyribonuclease V, subunit A; PFAM: UvrD/REP helicase; KEGG: rpc:RPC_0387 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.639 |
| RPE_0460 | recO | RPE_0460 | RPE_3018 | DNA helicase/exodeoxyribonuclease V, subunit A; PFAM: UvrD/REP helicase; KEGG: rpc:RPC_0387 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.777 |
| RPE_0460 | secE | RPE_0460 | RPE_3609 | DNA helicase/exodeoxyribonuclease V, subunit A; PFAM: UvrD/REP helicase; KEGG: rpc:RPC_0387 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. | Protein translocase subunit secE/sec61 gamma; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.500 |
| RPE_0503 | RPE_0460 | RPE_0503 | RPE_0460 | PFAM: Glutathione S-transferase, C-terminal domain; KEGG: rpc:RPC_0439 glutathione S-transferase-like. | DNA helicase/exodeoxyribonuclease V, subunit A; PFAM: UvrD/REP helicase; KEGG: rpc:RPC_0387 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. | 0.731 |
| RPE_0503 | RPE_3282 | RPE_0503 | RPE_3282 | PFAM: Glutathione S-transferase, C-terminal domain; KEGG: rpc:RPC_0439 glutathione S-transferase-like. | Regulatory inactivation of DnaA Hda protein; KEGG: rpc:RPC_2328 chromosomal replication initiator, DnaA; Belongs to the DnaA family. | 0.623 |
| RPE_0503 | RPE_4131 | RPE_0503 | RPE_4131 | PFAM: Glutathione S-transferase, C-terminal domain; KEGG: rpc:RPC_0439 glutathione S-transferase-like. | PFAM: protein of unknown function DUF1013; KEGG: rpa:RPA4272 hypothetical protein. | 0.655 |
| RPE_0503 | recO | RPE_0503 | RPE_3018 | PFAM: Glutathione S-transferase, C-terminal domain; KEGG: rpc:RPC_0439 glutathione S-transferase-like. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.678 |
| RPE_3282 | RPE_0460 | RPE_3282 | RPE_0460 | Regulatory inactivation of DnaA Hda protein; KEGG: rpc:RPC_2328 chromosomal replication initiator, DnaA; Belongs to the DnaA family. | DNA helicase/exodeoxyribonuclease V, subunit A; PFAM: UvrD/REP helicase; KEGG: rpc:RPC_0387 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. | 0.524 |
| RPE_3282 | RPE_0503 | RPE_3282 | RPE_0503 | Regulatory inactivation of DnaA Hda protein; KEGG: rpc:RPC_2328 chromosomal replication initiator, DnaA; Belongs to the DnaA family. | PFAM: Glutathione S-transferase, C-terminal domain; KEGG: rpc:RPC_0439 glutathione S-transferase-like. | 0.623 |
| RPE_3282 | RPE_4131 | RPE_3282 | RPE_4131 | Regulatory inactivation of DnaA Hda protein; KEGG: rpc:RPC_2328 chromosomal replication initiator, DnaA; Belongs to the DnaA family. | PFAM: protein of unknown function DUF1013; KEGG: rpa:RPA4272 hypothetical protein. | 0.466 |
| RPE_3282 | recF | RPE_3282 | RPE_0003 | Regulatory inactivation of DnaA Hda protein; KEGG: rpc:RPC_2328 chromosomal replication initiator, DnaA; Belongs to the DnaA family. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.814 |
| RPE_3282 | recO | RPE_3282 | RPE_3018 | Regulatory inactivation of DnaA Hda protein; KEGG: rpc:RPC_2328 chromosomal replication initiator, DnaA; Belongs to the DnaA family. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.779 |
| RPE_3282 | secE | RPE_3282 | RPE_3609 | Regulatory inactivation of DnaA Hda protein; KEGG: rpc:RPC_2328 chromosomal replication initiator, DnaA; Belongs to the DnaA family. | Protein translocase subunit secE/sec61 gamma; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.428 |
| RPE_4131 | RPE_0460 | RPE_4131 | RPE_0460 | PFAM: protein of unknown function DUF1013; KEGG: rpa:RPA4272 hypothetical protein. | DNA helicase/exodeoxyribonuclease V, subunit A; PFAM: UvrD/REP helicase; KEGG: rpc:RPC_0387 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. | 0.681 |