STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPE_3199KEGG: afu:AF2100 acetolactate synthase large subunit. (110 aa)    
Predicted Functional Partners:
RPE_3200
PFAM: thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: afu:AF2100 acetolactate synthase large subunit.
     0.979
RPE_2189
TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: rpc:RPC_3253 acetolactate synthase, small subunit.
  
 
 0.914
RPE_3197
PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: sil:SPO0796 hypothetical protein.
 
   
 0.822
RPE_3198
PFAM: Bile acid:sodium symporter; KEGG: sil:SPO0797 bile acid transporter family protein.
 
    0.821
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.687
RPE_3201
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: sme:SMb21530 acetolactate synthase large subunit.
       0.551
RPE_0683
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin).
  
  
 0.527
RPE_3983
PFAM: thioesterase superfamily protein; KEGG: rpd:RPD_2382 thioesterase superfamily.
  
     0.503
RPE_2261
Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: rpd:RPD_2216 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
  
 0.498
RPE_3688
PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: rpc:RPC_3648 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
  
 0.498
Your Current Organism:
Rhodopseudomonas palustris BisA53
NCBI taxonomy Id: 316055
Other names: R. palustris BisA53, Rhodopseudomonas palustris str. BisA53, Rhodopseudomonas palustris strain BisA53
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