node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPE_1228 | RPE_3101 | RPE_1228 | RPE_3101 | PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase; KEGG: rpb:RPB_0946 iron-containing alcohol dehydrogenase. | KEGG: rpc:RPC_2980 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL. | 0.609 |
RPE_1228 | RPE_3102 | RPE_1228 | RPE_3102 | PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase; KEGG: rpb:RPB_0946 iron-containing alcohol dehydrogenase. | Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | 0.655 |
RPE_1228 | RPE_3204 | RPE_1228 | RPE_3204 | PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase; KEGG: rpb:RPB_0946 iron-containing alcohol dehydrogenase. | KEGG: dsy:DSY0244 hypothetical protein. | 0.963 |
RPE_1228 | tal | RPE_1228 | RPE_3708 | PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase; KEGG: rpb:RPB_0946 iron-containing alcohol dehydrogenase. | Glucose-6-phosphate isomerase / transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. | 0.462 |
RPE_1805 | RPE_3204 | RPE_1805 | RPE_3204 | Ethanolamine ammonia-lyase heavy chain; PFAM: Ethanolamine ammonia lyase large subunit; KEGG: rpc:RPC_1711 ethanolamine ammonia lyase large subunit. | KEGG: dsy:DSY0244 hypothetical protein. | 0.544 |
RPE_3101 | RPE_1228 | RPE_3101 | RPE_1228 | KEGG: rpc:RPC_2980 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL. | PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase; KEGG: rpb:RPB_0946 iron-containing alcohol dehydrogenase. | 0.609 |
RPE_3101 | RPE_3102 | RPE_3101 | RPE_3102 | KEGG: rpc:RPC_2980 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL. | Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | 0.996 |
RPE_3101 | RPE_3203 | RPE_3101 | RPE_3203 | KEGG: rpc:RPC_2980 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL. | succinyl-CoA synthetase (ADP-forming) beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; KEGG: ttj:TTHA0538 succinyl-CoA synthetase beta chain. | 0.811 |
RPE_3101 | RPE_3204 | RPE_3101 | RPE_3204 | KEGG: rpc:RPC_2980 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL. | KEGG: dsy:DSY0244 hypothetical protein. | 0.660 |
RPE_3101 | RPE_4908 | RPE_3101 | RPE_4908 | KEGG: rpc:RPC_2980 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL. | PFAM: iron-containing alcohol dehydrogenase; KEGG: rpa:RPA4822 possible alcohol dehydrogenase. | 0.599 |
RPE_3101 | sucD-2 | RPE_3101 | RPE_3202 | KEGG: rpc:RPC_2980 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.821 |
RPE_3101 | tal | RPE_3101 | RPE_3708 | KEGG: rpc:RPC_2980 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL. | Glucose-6-phosphate isomerase / transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. | 0.710 |
RPE_3102 | RPE_1228 | RPE_3102 | RPE_1228 | Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase; KEGG: rpb:RPB_0946 iron-containing alcohol dehydrogenase. | 0.655 |
RPE_3102 | RPE_3101 | RPE_3102 | RPE_3101 | Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | KEGG: rpc:RPC_2980 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL. | 0.996 |
RPE_3102 | RPE_3204 | RPE_3102 | RPE_3204 | Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | KEGG: dsy:DSY0244 hypothetical protein. | 0.702 |
RPE_3102 | RPE_4908 | RPE_3102 | RPE_4908 | Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. | PFAM: iron-containing alcohol dehydrogenase; KEGG: rpa:RPA4822 possible alcohol dehydrogenase. | 0.645 |
RPE_3201 | RPE_3203 | RPE_3201 | RPE_3203 | PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: sme:SMb21530 acetolactate synthase large subunit. | succinyl-CoA synthetase (ADP-forming) beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; KEGG: ttj:TTHA0538 succinyl-CoA synthetase beta chain. | 0.616 |
RPE_3201 | RPE_3204 | RPE_3201 | RPE_3204 | PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: sme:SMb21530 acetolactate synthase large subunit. | KEGG: dsy:DSY0244 hypothetical protein. | 0.729 |
RPE_3201 | sucD-2 | RPE_3201 | RPE_3202 | PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: sme:SMb21530 acetolactate synthase large subunit. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.615 |
RPE_3203 | RPE_3101 | RPE_3203 | RPE_3101 | succinyl-CoA synthetase (ADP-forming) beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein; KEGG: ttj:TTHA0538 succinyl-CoA synthetase beta chain. | KEGG: rpc:RPC_2980 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL. | 0.811 |