| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_0019 | RPE_1954 | RPE_0019 | RPE_1954 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | KEGG: rpd:RPD_2023 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein. | 0.928 |
| RPE_0019 | RPE_4357 | RPE_0019 | RPE_4357 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.508 |
| RPE_0019 | panB | RPE_0019 | RPE_3348 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.929 |
| RPE_0019 | panC | RPE_0019 | RPE_3413 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.929 |
| RPE_1423 | RPE_2261 | RPE_1423 | RPE_2261 | KEGG: rpc:RPC_1388 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV. | Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: rpd:RPD_2216 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.981 |
| RPE_1423 | RPE_3688 | RPE_1423 | RPE_3688 | KEGG: rpc:RPC_1388 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV. | PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: rpc:RPC_3648 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.981 |
| RPE_1423 | ilvD | RPE_1423 | RPE_4363 | KEGG: rpc:RPC_1388 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV. | KEGG: bmb:BruAb1_0096 IlvD, dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.983 |
| RPE_1423 | panB | RPE_1423 | RPE_3348 | KEGG: rpc:RPC_1388 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.924 |
| RPE_1954 | RPE_0019 | RPE_1954 | RPE_0019 | KEGG: rpd:RPD_2023 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.928 |
| RPE_1954 | RPE_4357 | RPE_1954 | RPE_4357 | KEGG: rpd:RPD_2023 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein. | GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.508 |
| RPE_1954 | panB | RPE_1954 | RPE_3348 | KEGG: rpd:RPD_2023 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.929 |
| RPE_1954 | panC | RPE_1954 | RPE_3413 | KEGG: rpd:RPD_2023 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.929 |
| RPE_2261 | RPE_1423 | RPE_2261 | RPE_1423 | Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: rpd:RPD_2216 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | KEGG: rpc:RPC_1388 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV. | 0.981 |
| RPE_2261 | RPE_3688 | RPE_2261 | RPE_3688 | Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: rpd:RPD_2216 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: rpc:RPC_3648 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.917 |
| RPE_2261 | RPE_4357 | RPE_2261 | RPE_4357 | Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: rpd:RPD_2216 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.561 |
| RPE_2261 | ilvD | RPE_2261 | RPE_4363 | Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: rpd:RPD_2216 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | KEGG: bmb:BruAb1_0096 IlvD, dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.917 |
| RPE_2261 | panB | RPE_2261 | RPE_3348 | Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: rpd:RPD_2216 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.918 |
| RPE_3349 | panB | RPE_3349 | RPE_3348 | PFAM: NnrUfamily protein; KEGG: rpc:RPC_2275 NnrU. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.875 |
| RPE_3688 | RPE_1423 | RPE_3688 | RPE_1423 | PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: rpc:RPC_3648 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | KEGG: rpc:RPC_1388 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV. | 0.981 |
| RPE_3688 | RPE_2261 | RPE_3688 | RPE_2261 | PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: rpc:RPC_3648 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: rpd:RPD_2216 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.917 |