| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_0302 | bioD | RPE_0302 | RPE_3401 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.584 |
| RPE_0915 | RPE_1359 | RPE_0915 | RPE_1359 | PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | KEGG: rpc:RPC_1325 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III. | 0.657 |
| RPE_0915 | RPE_3191 | RPE_0915 | RPE_3191 | PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | PFAM: Radical SAM domain protein; KEGG: rpa:RPA2614 hypothetical protein. | 0.815 |
| RPE_0915 | RPE_3400 | RPE_0915 | RPE_3400 | PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: nha:Nham_2816 8-amino-7-oxononanoate synthase. | 0.662 |
| RPE_0915 | RPE_4787 | RPE_0915 | RPE_4787 | PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | KEGG: rpa:RPA0854 5-aminolevulinic acid synthase (ALAS); TIGRFAM: 5-aminolevulinic acid synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; aminotransferase class-III. | 0.658 |
| RPE_0915 | bioB | RPE_0915 | RPE_2208 | PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.864 |
| RPE_0915 | bioD | RPE_0915 | RPE_3401 | PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.909 |
| RPE_1359 | RPE_0915 | RPE_1359 | RPE_0915 | KEGG: rpc:RPC_1325 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III. | PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.657 |
| RPE_1359 | RPE_3191 | RPE_1359 | RPE_3191 | KEGG: rpc:RPC_1325 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III. | PFAM: Radical SAM domain protein; KEGG: rpa:RPA2614 hypothetical protein. | 0.745 |
| RPE_1359 | RPE_3402 | RPE_1359 | RPE_3402 | KEGG: rpc:RPC_1325 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III. | Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: nha:Nham_2814 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.758 |
| RPE_1359 | RPE_4787 | RPE_1359 | RPE_4787 | KEGG: rpc:RPC_1325 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III. | KEGG: rpa:RPA0854 5-aminolevulinic acid synthase (ALAS); TIGRFAM: 5-aminolevulinic acid synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; aminotransferase class-III. | 0.902 |
| RPE_1359 | bioB | RPE_1359 | RPE_2208 | KEGG: rpc:RPC_1325 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.816 |
| RPE_1359 | bioD | RPE_1359 | RPE_3401 | KEGG: rpc:RPC_1325 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.918 |
| RPE_3191 | RPE_0915 | RPE_3191 | RPE_0915 | PFAM: Radical SAM domain protein; KEGG: rpa:RPA2614 hypothetical protein. | PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.815 |
| RPE_3191 | RPE_1359 | RPE_3191 | RPE_1359 | PFAM: Radical SAM domain protein; KEGG: rpa:RPA2614 hypothetical protein. | KEGG: rpc:RPC_1325 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III. | 0.745 |
| RPE_3191 | RPE_3400 | RPE_3191 | RPE_3400 | PFAM: Radical SAM domain protein; KEGG: rpa:RPA2614 hypothetical protein. | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: nha:Nham_2816 8-amino-7-oxononanoate synthase. | 0.745 |
| RPE_3191 | RPE_3402 | RPE_3191 | RPE_3402 | PFAM: Radical SAM domain protein; KEGG: rpa:RPA2614 hypothetical protein. | Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: nha:Nham_2814 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.815 |
| RPE_3191 | RPE_4787 | RPE_3191 | RPE_4787 | PFAM: Radical SAM domain protein; KEGG: rpa:RPA2614 hypothetical protein. | KEGG: rpa:RPA0854 5-aminolevulinic acid synthase (ALAS); TIGRFAM: 5-aminolevulinic acid synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; aminotransferase class-III. | 0.745 |
| RPE_3191 | bioD | RPE_3191 | RPE_3401 | PFAM: Radical SAM domain protein; KEGG: rpa:RPA2614 hypothetical protein. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.908 |
| RPE_3400 | RPE_0915 | RPE_3400 | RPE_0915 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: nha:Nham_2816 8-amino-7-oxononanoate synthase. | PFAM: aminotransferase class-III; KEGG: rpc:RPC_0894 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.662 |