| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_0114 | RPE_4151 | RPE_0114 | RPE_4151 | PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bja:blr0103 probable oxidoreductase. | PFAM: aldo/keto reductase; KEGG: rpd:RPD_3895 aldo/keto reductase. | 0.510 |
| RPE_0114 | RPE_4552 | RPE_0114 | RPE_4552 | PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bja:blr0103 probable oxidoreductase. | HAD-superfamily hydrolase, subfamily IIB; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. | 0.470 |
| RPE_1259 | RPE_3773 | RPE_1259 | RPE_3773 | Sulfite reductase (NADPH) alpha subunit; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; KEGG: rpb:RPB_1753 oxidoreductase, FAD/NAD(P)-binding. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.902 |
| RPE_1259 | RPE_4151 | RPE_1259 | RPE_4151 | Sulfite reductase (NADPH) alpha subunit; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; KEGG: rpb:RPB_1753 oxidoreductase, FAD/NAD(P)-binding. | PFAM: aldo/keto reductase; KEGG: rpd:RPD_3895 aldo/keto reductase. | 0.665 |
| RPE_2082 | RPE_4151 | RPE_2082 | RPE_4151 | PFAM: aldo/keto reductase; KEGG: rpc:RPC_4894 aldo/keto reductase. | PFAM: aldo/keto reductase; KEGG: rpd:RPD_3895 aldo/keto reductase. | 0.671 |
| RPE_2082 | tal | RPE_2082 | RPE_3708 | PFAM: aldo/keto reductase; KEGG: rpc:RPC_4894 aldo/keto reductase. | Glucose-6-phosphate isomerase / transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. | 0.458 |
| RPE_3266 | RPE_4151 | RPE_3266 | RPE_4151 | PFAM: Alcohol dehydrogenase, zinc-binding domain protein; KEGG: rpc:RPC_3068 alcohol dehydrogenase, zinc-binding. | PFAM: aldo/keto reductase; KEGG: rpd:RPD_3895 aldo/keto reductase. | 0.510 |
| RPE_3266 | RPE_4552 | RPE_3266 | RPE_4552 | PFAM: Alcohol dehydrogenase, zinc-binding domain protein; KEGG: rpc:RPC_3068 alcohol dehydrogenase, zinc-binding. | HAD-superfamily hydrolase, subfamily IIB; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. | 0.470 |
| RPE_3773 | RPE_1259 | RPE_3773 | RPE_1259 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Sulfite reductase (NADPH) alpha subunit; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; KEGG: rpb:RPB_1753 oxidoreductase, FAD/NAD(P)-binding. | 0.902 |
| RPE_3773 | RPE_4151 | RPE_3773 | RPE_4151 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: aldo/keto reductase; KEGG: rpd:RPD_3895 aldo/keto reductase. | 0.773 |
| RPE_3773 | tal | RPE_3773 | RPE_3708 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glucose-6-phosphate isomerase / transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. | 0.453 |
| RPE_4112 | RPE_4151 | RPE_4112 | RPE_4151 | PFAM: OsmC family protein; KEGG: rpc:RPC_3986 OsmC-like protein. | PFAM: aldo/keto reductase; KEGG: rpd:RPD_3895 aldo/keto reductase. | 0.591 |
| RPE_4112 | RPE_4552 | RPE_4112 | RPE_4552 | PFAM: OsmC family protein; KEGG: rpc:RPC_3986 OsmC-like protein. | HAD-superfamily hydrolase, subfamily IIB; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. | 0.509 |
| RPE_4151 | RPE_0114 | RPE_4151 | RPE_0114 | PFAM: aldo/keto reductase; KEGG: rpd:RPD_3895 aldo/keto reductase. | PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bja:blr0103 probable oxidoreductase. | 0.510 |
| RPE_4151 | RPE_1259 | RPE_4151 | RPE_1259 | PFAM: aldo/keto reductase; KEGG: rpd:RPD_3895 aldo/keto reductase. | Sulfite reductase (NADPH) alpha subunit; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; KEGG: rpb:RPB_1753 oxidoreductase, FAD/NAD(P)-binding. | 0.665 |
| RPE_4151 | RPE_2082 | RPE_4151 | RPE_2082 | PFAM: aldo/keto reductase; KEGG: rpd:RPD_3895 aldo/keto reductase. | PFAM: aldo/keto reductase; KEGG: rpc:RPC_4894 aldo/keto reductase. | 0.671 |
| RPE_4151 | RPE_3266 | RPE_4151 | RPE_3266 | PFAM: aldo/keto reductase; KEGG: rpd:RPD_3895 aldo/keto reductase. | PFAM: Alcohol dehydrogenase, zinc-binding domain protein; KEGG: rpc:RPC_3068 alcohol dehydrogenase, zinc-binding. | 0.510 |
| RPE_4151 | RPE_3773 | RPE_4151 | RPE_3773 | PFAM: aldo/keto reductase; KEGG: rpd:RPD_3895 aldo/keto reductase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.773 |
| RPE_4151 | RPE_4112 | RPE_4151 | RPE_4112 | PFAM: aldo/keto reductase; KEGG: rpd:RPD_3895 aldo/keto reductase. | PFAM: OsmC family protein; KEGG: rpc:RPC_3986 OsmC-like protein. | 0.591 |
| RPE_4151 | RPE_4152 | RPE_4151 | RPE_4152 | PFAM: aldo/keto reductase; KEGG: rpd:RPD_3895 aldo/keto reductase. | TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: rpc:RPC_4093 hypothetical protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | 0.532 |