| node1 | node2 | node1 annotation | node2 annotation | score |
| RPE_0602 | RPE_0635 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.935 |
| RPE_0602 | RPE_0766 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpc:RPC_0704 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 0.999 |
| RPE_0602 | RPE_2140 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | PFAM: FAD linked oxidase domain protein; KEGG: rpc:RPC_3276 FAD linked oxidase-like. | 0.904 |
| RPE_0602 | RPE_2614 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.941 |
| RPE_0602 | RPE_3057 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | PFAM: pyruvate kinase; KEGG: rpc:RPC_2956 pyruvate kinase; Belongs to the pyruvate kinase family. | 0.941 |
| RPE_0602 | RPE_3275 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)))/Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rpb:RPB_2497 bifunctional oxaloacetate decarboxylating malate dehydrogenase (NADP+)/phosphate acetyltransferase. | 0.956 |
| RPE_0602 | RPE_3438 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 2,3-dimethylmalate lyase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. | 0.900 |
| RPE_0602 | RPE_4110 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | PFAM: pyruvate kinase; KEGG: rpa:RPA4193 pyruvate kinase; Belongs to the pyruvate kinase family. | 0.941 |
| RPE_0602 | RPE_4170 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | L-lactate dehydrogenase (cytochrome); PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: rpd:RPD_3916 L-lactate dehydrogenase (cytochrome). | 0.926 |
| RPE_0635 | RPE_0602 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 0.935 |
| RPE_0635 | RPE_0766 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpc:RPC_0704 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 0.943 |
| RPE_0635 | RPE_2140 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | PFAM: FAD linked oxidase domain protein; KEGG: rpc:RPC_3276 FAD linked oxidase-like. | 0.902 |
| RPE_0635 | RPE_2614 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.955 |
| RPE_0635 | RPE_3057 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | PFAM: pyruvate kinase; KEGG: rpc:RPC_2956 pyruvate kinase; Belongs to the pyruvate kinase family. | 0.937 |
| RPE_0635 | RPE_3101 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | KEGG: rpc:RPC_2980 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL. | 0.917 |
| RPE_0635 | RPE_3275 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)))/Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rpb:RPB_2497 bifunctional oxaloacetate decarboxylating malate dehydrogenase (NADP+)/phosphate acetyltransferase. | 0.952 |
| RPE_0635 | RPE_3438 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 2,3-dimethylmalate lyase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. | 0.936 |
| RPE_0635 | RPE_4110 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | PFAM: pyruvate kinase; KEGG: rpa:RPA4193 pyruvate kinase; Belongs to the pyruvate kinase family. | 0.937 |
| RPE_0635 | RPE_4170 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | L-lactate dehydrogenase (cytochrome); PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: rpd:RPD_3916 L-lactate dehydrogenase (cytochrome). | 0.929 |
| RPE_0766 | RPE_0602 | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpc:RPC_0704 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: rpd:RPD_1532 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 0.999 |