| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_1945 | RPE_4172 | RPE_1945 | RPE_4172 | PFAM: protein of unknown function DUF1109; KEGG: sme:SMb20532 hypothetical protein. | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: rpc:RPC_4118 transcriptional regulator, XRE family. | 0.438 |
| RPE_2341 | RPE_4172 | RPE_2341 | RPE_4172 | PFAM: regulatory protein, TetR; KEGG: rpa:RPA3403 possible transcriptional regulator, TetR family. | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: rpc:RPC_4118 transcriptional regulator, XRE family. | 0.410 |
| RPE_2728 | RPE_4172 | RPE_2728 | RPE_4172 | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: rpc:RPC_2548 cystathionine beta-lyase. | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: rpc:RPC_4118 transcriptional regulator, XRE family. | 0.455 |
| RPE_2728 | metZ | RPE_2728 | RPE_4877 | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: rpc:RPC_2548 cystathionine beta-lyase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.923 |
| RPE_4172 | RPE_1945 | RPE_4172 | RPE_1945 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: rpc:RPC_4118 transcriptional regulator, XRE family. | PFAM: protein of unknown function DUF1109; KEGG: sme:SMb20532 hypothetical protein. | 0.438 |
| RPE_4172 | RPE_2341 | RPE_4172 | RPE_2341 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: rpc:RPC_4118 transcriptional regulator, XRE family. | PFAM: regulatory protein, TetR; KEGG: rpa:RPA3403 possible transcriptional regulator, TetR family. | 0.410 |
| RPE_4172 | RPE_2728 | RPE_4172 | RPE_2728 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: rpc:RPC_4118 transcriptional regulator, XRE family. | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: rpc:RPC_2548 cystathionine beta-lyase. | 0.455 |
| RPE_4172 | RPE_4173 | RPE_4172 | RPE_4173 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: rpc:RPC_4118 transcriptional regulator, XRE family. | TIGRFAM: small GTP-binding protein; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; elongation factor G, domain IV; KEGG: rpc:RPC_4119 small GTP-binding protein domain. | 0.591 |
| RPE_4172 | aroE | RPE_4172 | RPE_4171 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: rpc:RPC_4118 transcriptional regulator, XRE family. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.874 |
| RPE_4172 | metZ | RPE_4172 | RPE_4877 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: rpc:RPC_4118 transcriptional regulator, XRE family. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.455 |
| RPE_4173 | RPE_4172 | RPE_4173 | RPE_4172 | TIGRFAM: small GTP-binding protein; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; elongation factor G, domain IV; KEGG: rpc:RPC_4119 small GTP-binding protein domain. | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: rpc:RPC_4118 transcriptional regulator, XRE family. | 0.591 |
| RPE_4173 | aroE | RPE_4173 | RPE_4171 | TIGRFAM: small GTP-binding protein; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; elongation factor G, domain IV; KEGG: rpc:RPC_4119 small GTP-binding protein domain. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.670 |
| aroE | RPE_4172 | RPE_4171 | RPE_4172 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: rpc:RPC_4118 transcriptional regulator, XRE family. | 0.874 |
| aroE | RPE_4173 | RPE_4171 | RPE_4173 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | TIGRFAM: small GTP-binding protein; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; elongation factor G, domain IV; KEGG: rpc:RPC_4119 small GTP-binding protein domain. | 0.670 |
| metZ | RPE_2728 | RPE_4877 | RPE_2728 | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: rpc:RPC_2548 cystathionine beta-lyase. | 0.923 |
| metZ | RPE_4172 | RPE_4877 | RPE_4172 | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: rpc:RPC_4118 transcriptional regulator, XRE family. | 0.455 |