| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_1762 | RPE_1763 | RPE_1762 | RPE_1763 | Sulfate adenylyltransferase subunit 2; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: rpc:RPC_4016 phosphoadenosine phosphosulfate reductase. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.976 |
| RPE_1762 | RPE_1767 | RPE_1762 | RPE_1767 | Sulfate adenylyltransferase subunit 2; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: rpc:RPC_4016 phosphoadenosine phosphosulfate reductase. | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | 0.978 |
| RPE_1762 | cysC | RPE_1762 | RPE_0333 | Sulfate adenylyltransferase subunit 2; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: rpc:RPC_4016 phosphoadenosine phosphosulfate reductase. | Sulfate adenylyltransferase subunit 1 / adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
| RPE_1762 | cysC-2 | RPE_1762 | RPE_1761 | Sulfate adenylyltransferase subunit 2; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: rpc:RPC_4016 phosphoadenosine phosphosulfate reductase. | Sulfate adenylyltransferase subunit 1 / adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.999 |
| RPE_1762 | cysD | RPE_1762 | RPE_0334 | Sulfate adenylyltransferase subunit 2; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: rpc:RPC_4016 phosphoadenosine phosphosulfate reductase. | KEGG: rpc:RPC_0063 sulfate adenylyltransferase, small subunit; TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase. | 0.911 |
| RPE_1762 | cysQ | RPE_1762 | RPE_4286 | Sulfate adenylyltransferase subunit 2; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: rpc:RPC_4016 phosphoadenosine phosphosulfate reductase. | Inositol monophosphatase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.944 |
| RPE_1763 | RPE_1762 | RPE_1763 | RPE_1762 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Sulfate adenylyltransferase subunit 2; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: rpc:RPC_4016 phosphoadenosine phosphosulfate reductase. | 0.976 |
| RPE_1763 | RPE_1767 | RPE_1763 | RPE_1767 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | 0.991 |
| RPE_1763 | cysC | RPE_1763 | RPE_0333 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Sulfate adenylyltransferase subunit 1 / adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.976 |
| RPE_1763 | cysC-2 | RPE_1763 | RPE_1761 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Sulfate adenylyltransferase subunit 1 / adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.990 |
| RPE_1763 | cysD | RPE_1763 | RPE_0334 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | KEGG: rpc:RPC_0063 sulfate adenylyltransferase, small subunit; TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase. | 0.944 |
| RPE_1763 | cysQ | RPE_1763 | RPE_4286 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Inositol monophosphatase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.504 |
| RPE_1767 | RPE_1762 | RPE_1767 | RPE_1762 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | Sulfate adenylyltransferase subunit 2; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: rpc:RPC_4016 phosphoadenosine phosphosulfate reductase. | 0.978 |
| RPE_1767 | RPE_1763 | RPE_1767 | RPE_1763 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.991 |
| RPE_1767 | cysC | RPE_1767 | RPE_0333 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | Sulfate adenylyltransferase subunit 1 / adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
| RPE_1767 | cysC-2 | RPE_1767 | RPE_1761 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | Sulfate adenylyltransferase subunit 1 / adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.999 |
| RPE_1767 | cysD | RPE_1767 | RPE_0334 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | KEGG: rpc:RPC_0063 sulfate adenylyltransferase, small subunit; TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase. | 0.939 |
| RPE_1767 | cysQ | RPE_1767 | RPE_4286 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | Inositol monophosphatase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.934 |
| RPE_4285 | RPE_4786 | RPE_4285 | RPE_4786 | KEGG: rpc:RPC_4248 hypothetical protein. | Periplasmic sensor hybrid histidine kinase; PFAM: Na+/solute symporter; response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: rpc:RPC_4823 periplasmic sensor hybrid histidine kinase. | 0.422 |
| RPE_4285 | cysQ | RPE_4285 | RPE_4286 | KEGG: rpc:RPC_4248 hypothetical protein. | Inositol monophosphatase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.567 |