| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_0637 | RPE_4380 | RPE_0637 | RPE_4380 | Methyltransferase small; PFAM: putative RNA methylase; methyltransferase small; ribosomal L11 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: mth:MTH1329 methyltransferase related protein. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.577 |
| RPE_0928 | RPE_4380 | RPE_0928 | RPE_4380 | Modification methylase, HemK family; KEGG: bja:blr7474 hypothetical adenine-specific methylase; TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; Belongs to the protein N5-glutamine methyltransferase family. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.501 |
| RPE_1031 | RPE_4380 | RPE_1031 | RPE_4380 | Hypothetical protein; KEGG: hch:HCH_01987 probable phage protein. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.537 |
| RPE_2445 | RPE_4380 | RPE_2445 | RPE_4380 | KEGG: nha:Nham_4459 hypothetical protein. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.537 |
| RPE_4380 | RPE_0637 | RPE_4380 | RPE_0637 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Methyltransferase small; PFAM: putative RNA methylase; methyltransferase small; ribosomal L11 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: mth:MTH1329 methyltransferase related protein. | 0.577 |
| RPE_4380 | RPE_0928 | RPE_4380 | RPE_0928 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Modification methylase, HemK family; KEGG: bja:blr7474 hypothetical adenine-specific methylase; TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; Belongs to the protein N5-glutamine methyltransferase family. | 0.501 |
| RPE_4380 | RPE_1031 | RPE_4380 | RPE_1031 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Hypothetical protein; KEGG: hch:HCH_01987 probable phage protein. | 0.537 |
| RPE_4380 | RPE_2445 | RPE_4380 | RPE_2445 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | KEGG: nha:Nham_4459 hypothetical protein. | 0.537 |
| RPE_4380 | RPE_4381 | RPE_4380 | RPE_4381 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | PFAM: FAD linked oxidase domain protein; KEGG: rpc:RPC_4322 FAD linked oxidase-like. | 0.719 |
| RPE_4380 | aroE | RPE_4380 | RPE_4171 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.553 |
| RPE_4380 | glmS | RPE_4380 | RPE_2786 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.625 |
| RPE_4380 | glyA | RPE_4380 | RPE_2808 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.798 |
| RPE_4380 | prmC | RPE_4380 | RPE_0161 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Modification methylase, HemK family; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.827 |
| RPE_4380 | rpoZ | RPE_4380 | RPE_3027 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.537 |
| RPE_4381 | RPE_4380 | RPE_4381 | RPE_4380 | PFAM: FAD linked oxidase domain protein; KEGG: rpc:RPC_4322 FAD linked oxidase-like. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.719 |
| aroE | RPE_4380 | RPE_4171 | RPE_4380 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.553 |
| glmS | RPE_4380 | RPE_2786 | RPE_4380 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.625 |
| glyA | RPE_4380 | RPE_2808 | RPE_4380 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.798 |
| prmC | RPE_4380 | RPE_0161 | RPE_4380 | Modification methylase, HemK family; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.827 |
| rpoZ | RPE_4380 | RPE_3027 | RPE_4380 | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.537 |