STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPE_4440HtpX-2 peptidase. Metallo peptidase. MEROPS family M48B; PFAM: peptidase M48, Ste24p; KEGG: rpb:RPB_4314 peptidase M48, Ste24p. (370 aa)    
Predicted Functional Partners:
RPE_4439
Hypothetical protein.
       0.773
RPE_4441
PFAM: LemA family protein; KEGG: rpb:RPB_4313 LemA.
 
    0.659
RPE_4438
KEGG: rpc:RPC_4378 hypothetical protein.
       0.610
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.590
RPE_0410
PFAM: Thioredoxin domain; KEGG: rpa:RPA0267 possible thioredoxin.
  
  
 0.550
RPE_3791
PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: rpd:RPD_1895 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
  
 0.531
RPE_4437
KEGG: rpc:RPC_4379 hypothetical protein.
       0.500
RPE_0306
PFAM: protein of unknown function UPF0005; KEGG: rpc:RPC_0200 protein of unknown function UPF0005; Belongs to the BI1 family.
  
  
 0.484
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.427
RPE_1125
PFAM: ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: rpb:RPB_3063 ATPase.
   
 
 0.417
Your Current Organism:
Rhodopseudomonas palustris BisA53
NCBI taxonomy Id: 316055
Other names: R. palustris BisA53, Rhodopseudomonas palustris str. BisA53, Rhodopseudomonas palustris strain BisA53
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