STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPE_4592PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: rpc:RPC_1138 chaperone DnaJ-like. (322 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 0.991
RPE_0414
KEGG: rpc:RPC_0260 molecular chaperone, HSP70 class.
  
 0.962
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
 
 0.953
RPE_2484
PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: rpd:RPD_3368 ATP-binding region, ATPase-like.
 
 0.924
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 0.913
RPE_2828
PFAM: regulatory protein, MerR; KEGG: rpc:RPC_2678 transcriptional regulator, MerR family.
  
 
 0.901
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
 
 0.885
RPE_0771
PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: bja:blr6465 putative steroid monooxygenase.
   
 
 0.881
rplN
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.879
rplQ
PFAM: ribosomal protein L17; KEGG: rpd:RPD_3159 ribosomal protein L17.
  
   0.878
Your Current Organism:
Rhodopseudomonas palustris BisA53
NCBI taxonomy Id: 316055
Other names: R. palustris BisA53, Rhodopseudomonas palustris str. BisA53, Rhodopseudomonas palustris strain BisA53
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