| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPE_0683 | RPE_4775 | RPE_0683 | RPE_4775 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin). | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rpc:RPC_4812 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.412 |
| RPE_0683 | folD | RPE_0683 | RPE_0047 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin). | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.503 |
| RPE_0683 | pheT | RPE_0683 | RPE_0493 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin). | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: rpc:RPC_0444 phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.749 |
| RPE_1070 | RPE_4775 | RPE_1070 | RPE_4775 | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: rpc:RPC_1152 5'-nucleotidase-like; Belongs to the 5'-nucleotidase family. | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rpc:RPC_4812 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.422 |
| RPE_2330 | RPE_4775 | RPE_2330 | RPE_4775 | PFAM: Rhomboid family protein; KEGG: rpc:RPC_3129 rhomboid-like protein. | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rpc:RPC_4812 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.769 |
| RPE_3073 | RPE_4775 | RPE_3073 | RPE_4775 | Sulfate thiol esterase SoxB; TIGRFAM: Twin-arginine translocation pathway signal; PFAM: 5'-Nucleotidase domain protein; KEGG: rpb:RPB_4369 twin-arginine translocation pathway signal; Belongs to the 5'-nucleotidase family. | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rpc:RPC_4812 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.422 |
| RPE_4774 | RPE_4775 | RPE_4774 | RPE_4775 | TIGRFAM: conserved hypothetical protein; PFAM: metallophosphoesterase; KEGG: rpc:RPC_4811 hypothetical protein. | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rpc:RPC_4812 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.875 |
| RPE_4774 | folD | RPE_4774 | RPE_0047 | TIGRFAM: conserved hypothetical protein; PFAM: metallophosphoesterase; KEGG: rpc:RPC_4811 hypothetical protein. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.715 |
| RPE_4775 | RPE_0683 | RPE_4775 | RPE_0683 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rpc:RPC_4812 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin). | 0.412 |
| RPE_4775 | RPE_1070 | RPE_4775 | RPE_1070 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rpc:RPC_4812 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: rpc:RPC_1152 5'-nucleotidase-like; Belongs to the 5'-nucleotidase family. | 0.422 |
| RPE_4775 | RPE_2330 | RPE_4775 | RPE_2330 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rpc:RPC_4812 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | PFAM: Rhomboid family protein; KEGG: rpc:RPC_3129 rhomboid-like protein. | 0.769 |
| RPE_4775 | RPE_3073 | RPE_4775 | RPE_3073 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rpc:RPC_4812 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Sulfate thiol esterase SoxB; TIGRFAM: Twin-arginine translocation pathway signal; PFAM: 5'-Nucleotidase domain protein; KEGG: rpb:RPB_4369 twin-arginine translocation pathway signal; Belongs to the 5'-nucleotidase family. | 0.422 |
| RPE_4775 | RPE_4774 | RPE_4775 | RPE_4774 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rpc:RPC_4812 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | TIGRFAM: conserved hypothetical protein; PFAM: metallophosphoesterase; KEGG: rpc:RPC_4811 hypothetical protein. | 0.875 |
| RPE_4775 | folD | RPE_4775 | RPE_0047 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rpc:RPC_4812 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.932 |
| RPE_4775 | glyQ | RPE_4775 | RPE_4411 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rpc:RPC_4812 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Glycine--tRNA ligase; PFAM: glycyl-tRNA synthetase, alpha subunit; KEGG: rpd:RPD_1219 glycine--tRNA ligase. | 0.468 |
| RPE_4775 | moaC | RPE_4775 | RPE_2589 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rpc:RPC_4812 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.401 |
| RPE_4775 | pheT | RPE_4775 | RPE_0493 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rpc:RPC_4812 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: rpc:RPC_0444 phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.646 |
| RPE_4775 | purN | RPE_4775 | RPE_3285 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rpc:RPC_4812 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.920 |
| folD | RPE_0683 | RPE_0047 | RPE_0683 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rpc:RPC_0761 glutamate synthase (ferredoxin). | 0.503 |
| folD | RPE_4774 | RPE_0047 | RPE_4774 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | TIGRFAM: conserved hypothetical protein; PFAM: metallophosphoesterase; KEGG: rpc:RPC_4811 hypothetical protein. | 0.715 |